2,2,2-Trichloroethyl chloroformate

Product Details

CAS No:17341-93-4

MF:C3H2Cl4O2

Appearance:colorless or light-yellow transparent liquid

Specification:98.5%

Package:25kgs/drum

Supply Capacity:Tons

Synonyms:2,2,2-Trichloroethyl chloroformate; 2,2,2-trichloroethyl carbonochloridate;2,2,2-Trichloroethyl chloroforMate puruM, >=98.0% (NT);NALPHA-tert-Butoxycarbonyl-NEPSILON-trifluoroacetyl-D -lysine;(Trichloroethoxy)chloroformate;2,2,2-Trichloroethyl chloroformate ,97%;(2,2,2-Trichloroethoxy)formic acid chloride;(Carbonic acid 2,2,2-trichloroethyl) chloride;Chloridocarbonic acid 2,2,2-trichloroethyl ester; 2,2,2-Trichloroethyl chloroformate","2,2,2-Trichloroethyl chloroformate; 17341-93-4; Trichloroethyl chloroformate; Carbonochloridic acid, 2,2,2-trichloroethyl ester; 2,2,2-Trichloroethoxycarbonyl chloride; 99UY6LZN4R; NSC-152038; DTXSID3066188; DTXCID5035539; 241-363-7; 2,2,2-trichloroethylchloroformate; 2,2,2-trichloroethyl carbonochloridate; Troc-Cl; MFCD00000810; Formic acid, chloro-, 2,2,2-trichloroethyl ester; Chloroformic acid 2,2,2-trichloroethyl ester; 2,2,2-trichloroethylchloranuidylformate; beta,beta,beta-trichloroethyl chloroformate; C3H2Cl4O2; trichloroethoxycarbonyl chloride; Troc; TrocCl; EINECS 241-363-7; NSC 152038; chloro(2,2,2-trichloroethoxy)methanone; ClCO2CH2CCl3; trichloroethylchloroformate; UNII-99UY6LZN4R; SCHEMBL3023; LJCZNYWLQZZIOS-UHFFFAOYSA-; 2,2,2trichloroethyl chloroformate; 2,2,2-trichloroethyl-chloroformate; 2,2,2-trichloroethylchlorocarbonate; STR02674; 2,2,2-trichloroethyl chlorioformate; 2,2-Trichloroethoxycarbonyl chloride; 2,2,2-tri-chloroethyl chloroformate; 2,2,2-trichloroethyl chloro-formate; NSC152038; 2,2,2-trichloroethoxycarbonylchloride; 2,2,2-trichloroethyl chlorocarbonate; AKOS015917631; 2,2,2-trichioroethoxycarbonyl chloride; FT16026; 2,2,2-trichloroethyoxycarbonyl chloride; 2,2-TRICHLOROETHYL CHLOROFORMATE; 2,2,2-trichloroethyloxycarbonyl chloride; 2,2,2-Trichloroethyl chloridocarbonate #; Formic acid, 2,2,2-trichloroethyl ester; 2,2,2-Trichloroethyl chloroformate, 98%; DB-002395; NS00025690; ST51037946; chloroformic acid-2,2,2-trichloroethyl ester; C93433; Carbonochloridic acid,2,2-trichloroethyl ester; EN300-268363; Carbonochloridic acid 2,2,2-trichloroethyl ester; BETA,BETA,BETA-TRICHLOROETHOXYCARBONYL CHLORIDE; InChI=1/C3H2Cl4O2/c4-2(8)9-1-3(5,6)7/h1H2; 2,2,2-Trichloroethyl chloroformate, purum, >=98.0% (NT)",211.900,C3H2Cl4O2

2,2,2-Trichloroethyl Chloroformate (TCEF) is a crucial organic chemical raw material and intermediate. Due to its unique chemical properties arising from multiple reactive centers, it is insoluble in water but soluble in organic solvents like chloroform and ethanol. Safety precautions are necessary as it may decompose upon heating or contact with water, potentially releasing toxic gases.

The primary applications of 2,2,2-Trichloroethyl Chloroformate are concentrated in the pharmaceutical and organic synthesis fields:
1: Anti-Cancer Drug Precursor: It is a core raw material for the production of the anti-cancer drug Docetaxel (Taxotere).
2: Hydroxyl Protection: Utilized as a hydroxyl (OH) protecting group in academic and research settings (medicine/traditional Chinese medicine) for chemo-, regio-, and stereo-selective synthesis.
3: Organic Synthesis Reagent: Widely used as a selective reagent for acylation and dealkylation in various organic syntheses, serving as a key intermediate in agrochemicals, pharmaceuticals, and photoinitiators.
4: Analytical Applications: Used as a derivatization reagent in GC/MS analysis for measuring amphetamine-related drugs.
5: Other Uses: Historically utilized for its antiseptic, bactericidal, and fungicidal properties, including use in anti-fouling coatings for marine paint and as a stabilizer.