Nonaethylene glycol monomethyl ether

Product Details

CAS No:6048-68-6

MF:C19H40O10

Appearance:colorless or light-yellow transparent liquid

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Product application:Nonaethylene glycol monomethyl ether, 6048-68-6, m-PEG9-alcohol, Monodisperse PEG, Discrete PEG, mPEG9-OH, Methyl-PEG9-alcohol, PROTAC Linker, ADC Linkers, PEGylation reagent, Hydrophilic spacer, Pharmaceutical grade PEG, CAS 6048-68-6, Fine chemicals, Chemical intermediate, Non-ionic surfactant, High purity PEG derivatives, Research chemicals.

Synonyms:Nonaethylene glycol monomethyl ether; NONAETHYLENE GLYCOL MONOMETHYL ETHER;MPEG9-OH;MPEG-9;2,5,8,11,14,17,20,23,26-Nonaoxaoctacosan-28-ol;m-PEG9-alcohol;Methyl-PEG9-alcohol;O-metil-nonaetilenglicol;2,5,8,11,14,17,20,23,26-Nonaoxa-28-octacosanol; Nonaethylene Glycol Monomethyl Ether,O-methyl-nonaethyleneglycol,O-Methyl-nonaaethylenglykol,3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol,3,6,9,12,15,18,21,24,27-Nonaoxaoctacosanol,O-methyl-nonaaethylene glycol,2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-olNonaethylene glycol monomethyl ether; Nonaethylene Glycol Monomethyl Ether,"6048-68-6; Nonaethylene Glycol Monomethyl Ether; 2,5,8,11,14,17,20,23,26-nonaoxaoctacosan-28-ol; 2-[2-[2-[2-[2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethanol; O-methyl-nonaethyleneglycol; CHEBI:59168; DTXSID00462861; 2-(2-(2-(2-(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethanol; DTXCID90413680; VVHAVLIDQNWEKF-UHFFFAOYSA-N; m-PEG9-alcohol; mPEG9-OH; MFCD06797148; 2,5,8,11,14,17,20,23,26-Nonaoxa-28-octacosanol; mPEG9-Alcohol; C19H40O10; Methyl-PEG9-alcohol; O-methyl-nonaethyleneglyco; SCHEMBL679834; orb1909313; SCHEMBL5240827; 3,6,9,12,15,18,21,24,27-Nonaoxaoctacosan-1-ol; nonaethyleneglycol monomethyl ether; nonethylene glycol monomethyl ether; BCP11269; AKOS022174842; FM72952; AS-66955; BP-22071; DA-56243; SY054369; HY-120175; CS-0077091; N0699; NS00076621; C70275; Q27126506",428.500,C19H40O10,

 

Nonaethylene glycol monomethyl ether is a high-purity discrete polyethylene glycol derivative. Its molecular structure contains nine repeating ethylene glycol units, each terminally closed by a methyl group and ending with an active hydroxyl group. Due to its monodisperse molecular weight distribution rather than the traditional mixture of average molecular weights, it exhibits exceptional physicochemical stability in precision pharmaceutical synthesis and advanced materials modification. This product possesses good hydrophilicity and biocompatibility, making it a key raw material in modern drug delivery systems and bioconjugation technologies.

 

1. In pharmaceutical research and development, nonaethylene glycol monomethyl ether is often used as a crucial linker for conjugating small molecule drugs to biomacromolecules. Its discrete chain lengths ensure a high degree of consistency in the physicochemical properties of drug molecules, particularly in protein degradation-targeted chimeric technologies for cancer treatment, where it is a vital component for constructing hydrophilic spacing.

 

2. In biotechnology, nonaethylene glycol monomethyl ether is used to improve the pharmacokinetic properties of protein or peptide drugs. By introducing this long chain into drug molecules, the apparent molecular weight of the drug can be effectively increased, immunogenicity reduced, and the circulating half-life of the drug in the human body prolonged.

 

3. Nonaethylene glycol monomethyl ether can be used as a high-performance surfactant or surface treatment agent in materials science. Its polyether segments provide excellent wetting and dispersibility, and it is commonly used in electronic chemicals, advanced inks, and precision coatings to enhance the antistatic and hydrophilic properties of products.

 

4. As a chemical intermediate, the terminal hydroxyl groups of nonaethylene glycol monomethyl ether can be further converted into various functional groups such as toluenesulfonate, azide, carboxylic acid, or amino groups. This allows it to flexibly participate in the stepwise synthesis of more complex discrete polyethylene glycol derivatives, meeting the needs of customized chemical synthesis.