N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate

Product Details

CAS No:207915-99-9

MF:C5H12ClN2.PF6

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:UN 3261 8/PG III

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:CHLORO-N,N,N,N-TETRAMETHYLFORMA-MIDINIUM PF6;Chloro-N,N,N',N'-tetramethylformamidiniumhexafluo;N,N,N',N'-Tetramethylchloroformamidinium-hexafluorophosphate;N-(Chloro(diMethylaMino)Methylene)-N-MethylMethanaMiniuM hexafluorophosphate(V);Chloro-N,N,N′,N′-tetraMethylforMaMidiniuM hexafluorophosphate, >=98.0%;TCFH, >=98.0%;TCFH N,N,N‘,N‘-Tetramethylchloroformamidinium-hexafluorophosphe;Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate >=98.0% (T),"Chloro-N,N,N',N'-tetramethylformamidinium Hexafluorophosphate","207915-99-9; Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate; DTXSID50451023; DTXCID70401843; 627-919-5; 680-115-6; 94790-35-9; TCFH; N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate; N-(Chloro(dimethylamino)methylene)-N-methylmethanaminium hexafluorophosphate(V); N,N,N',N'-Tetramethylchloroformamidinium-hexafluorophosphate; Chloro-N,N,N',N'-tetramethyl-formamidinium Hexafluorophosphate; Methanaminium, N-[chloro(dimethylamino)methylene]-N-methyl-, hexafluorophosphate(1-) (1:1); MFCD01862891; [chloro(dimethylamino)methylidene]-dimethylazanium;hexafluorophosphate; [chloro(dimethylamino)methylene]-dimethyl-ammonium hexafluorophosphate; [chloro(dimethylamino)methylidene]-dimethylazanium,hexafluorophosphate; N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH); CUKNPSDEURGZCO-UHFFFAOYSA-N; TCFH, Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate; orb2939240; SCHEMBL3113482; SCHEMBL31329598; HIA91599; AC2489; AKOS015833813; CS-W012272; FC41882; HY-W011556; AS-17652; SY019094; C1957; EN300-7361941; tetra-methylchloroformamidinium hexafluorophosphate; Bis(dimethylamino)chlorocarbenium hexafluorophosphate; chloro-N,N,N',N'tetramethylformamidinium hexafluorophosphate; Chloro-N,N,N(2),N(2)-tetramethylformamidinium hexafluorophosphate; N-(chloro(dimethylamino)methylene)-N-methylmethanaminium hexafluorophosphate; [chloro(dimethylamino)methylidene]dimethylazanium; hexafluoro-lambda5-phosphanuide; Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate, 98.0% (T); N-(Chloro(dimethylamino)methylene)-N-methylmethanaminiumhexafluorophosphate(V); Chloro-N,N,N inverted exclamation mark ,N inverted exclamation mark -tetramethylformamidinium Hexafluorophosphate; N,N,N inverted exclamation mark(R),N inverted exclamation mark(R)-Tetramethylchloroformamidinium-hexafluorophosphate; TCFH;N,N,N',N'-Tetramethylchloroformamdnum hexafluorophosphate; Chloro(dimethylamino)-N,N-dimethylmethaniminium hexafluorophosphate",280.580,C5H12ClF6N2P,

Product application:N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate, TCFH reagent, CAS 207915-99-9, peptide coupling reagent, Suzhou Health Chemicals, TCFH manufacturer, amidation reagent for hindered carboxylic acids, esterification coupling reagent, Chloro-N,N,N',N'-tetramethylformamidinium hexafluorophosphate, high purity TCFH bulk supply, solid phase peptide synthesis reagents, onium salt coupling agent, CAS 94790-35-9

 

N,N,N',N'-Tetramethylchloroformamidinium hexafluorophosphate (TCFH) is predominantly utilized as a highly efficient coupling reagent in peptide synthesis (both SPPS and LPPS) and pharmaceutical chemical synthesis. It showcases outstanding performance in constructing difficult amide bonds involving highly sterically hindered carboxylic acids and low-nucleophilic amines or alcohols. TCFH serves as an economical and high-yield alternative for generating esters, thioesters, and ketones, making it a staple reagent in modern drug discovery and commercial chemical manufacturing.