N-Cbz-2-Phosphonoglycine trimethyl ester

Product Details

CAS No:88568-95-0

MF:C13H18NO7P

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:N-Cbz-2-phosphonoglycine Trimethyl EsterTrimethyl 2-(Carbobenzoxyamino)-2-phosphonoacetateTrimethyl 2-(Cbz-amino)-2-phosphonoacetate;(±)-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate,95%;(+/-)-Benzyloxycarbonyl-alfa-phosphonoglycinetrimethylester;N-Carbobenzoxy-2-phosphonoglycine Trimethyl Ester;(§1)-Methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphinyl)acetate, 95%;(+/-)-Cbz-alpha-phosphonoglycine;(+/-)-METHYL 2-BENZYLOXYCARBONYLAMINO-2-(DIMETHOXYPHOSPHINYL)ACETATE;DL-Z-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER; methyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethyl phosphono)acetate; methyl 2-(((benzyloxy)carbonyl)amino)-2-(dimethyl phosphono)acetate; RefChem:813003; 629-458-5; 88568-95-0; Methyl 2-(((benzyloxy)carbonyl)amino)-2-(dimethoxyphosphoryl)acetate; (+/-)-BENZYLOXYCARBONYL-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER; methyl 2-{[(benzyloxy)carbonyl]amino}-2-(dimethoxyphosphoryl)acetate; Methyl N-(benzyloxycarbonyl)-2-(dimethylphosphono)glycinate; MFCD00043304; C13H18NO7P; methyl 2-dimethoxyphosphoryl-2-(phenylmethoxycarbonylamino)acetate; Cbz-alpha-Phosphono-DL-glycine trimethyl ester; (+/-)-Cbz-alpha-phosphonoglycine trimethyl ester; Methyl 2-(benzyloxycarbonylamino)-2-dimethoxyphosphoryl-acetate; SCHEMBL187849; 100945-15-1; N-Benzyloxycarbonyl-2-phosphonoglycine trimethyl ester; AC-3439; methyl 2-benzyloxycarbonylamino-2(dimethoxyphosphinyl)acetate; ( inverted exclamation markA)-Z-|A-Phosphonoglycinetrimethyl ester; Trimethyl 2-; (+/-)-N-Cbz-alpha-phosphonoglycine Trimethyl Ester; orb2944150; GSYSFVSGPABNNL-UHFFFAOYSA-N; CS-D0335; Methyl ([(benzyloxy)carbonyl]amino)-(dimethoxyphosphoryl)acetate; METHYL 2-BENZYLOXYCARBONYLAMINO-2-(DIMETHOXYPHOSPHINYL)ACETATE; TCL-00005; Z-|A-Phosphonoglycine trimethyl ester; AKOS005146472; PB28987; PB46011; Z-alpha-Phosphonoglycine trimethyl ester; AS-11454; BP-21306; HY-33291; SY015068; FT-0684901; ST51007066; EN300-154444; Z-alpha-Phosphonoglycine trimethyl ester, 97%; F049045; (+/-)-Z-A-PHOSPHONOGLYCINE TRIMETHYL ESTER; methyl benzyloxycarbonylamino-(dimethoxyphosphoryl)acetate; (?)-Benzyloxycarbonyl-alpha-phosphonoglycine trimethyl ester; methyl benzyloxycarbonylamino-(dimethoxyphosphoryl)-acetate; N-(benzyloxycarbonyl)-alpha-phophonoglycine trimethyl ester; methyl {[(benzyloxy)carbonyl]amino}(dimethoxyphosphoryl)acetate; methyl {[benzyloxycarbonyl]amino}(dimethoxyphosphoryl)acetate; methyl 2-benzyloxycarbonylamino-2-(dimethoxyphosphoryl)acetate; methyl{[(benzyloxy)carbonyl]amino}(dimethoxyphosphoryl)acetate; methyl{[(benzyloxy)carbonyl]amino}-(dimethoxyphosphoryl)acetate; ( inverted exclamation markA)-Z-|A-phosphonoglycine trimethyl ester; methyl {[(benzyloxy)carbonyl]-amino}(dimethoxyphosphoryl)acetate; methyl 2-(((benzyloxy)carbonyl)amino)-2(dimethoxyphosphoryl)acetate; methyl 2-(benzyloxycarbonylamino)-2-(dimethoxyphosphoryl)acetate; methyl 2-(dimethoxycarbonyl)-2-[(phenylmethoxy)carbonylamino]acetate; N-(BENZYLOXYCARBONYL)-ALPHA-PHOSPHONOGLYCINE TRIMETHYL ESTER; methyl[bis(methyloxy)phosphoryl]({[(phenylmethyl)oxy]-carbonyl}amino)acetate; methyl[bis(methyloxy)phosphoryl]({[(phenylmethyl)oxy]carbonyl}amino)acetate; rac.-n-(benzyloxycarbonyl)-2-(dimethoxyphosphinyl)glycine methyl ester; BENZYLOXYCARBONYLAMINO-(DIMETHOXY-PHOSPHORYL)-ACETIC ACID METHYL ESTER

Product application:N-Cbz-2-Phosphonoglycine trimethyl ester,88568-95-0,Trimethyl N-(benzyloxycarbonyl)-2-phosphonoglycinate,Methyl (benzyloxycarbonylamino)(dimethoxyphosphoryl)acetate,Cbz-alpha-phosphonoglycine trimethyl ester,Horner-Wadsworth-Emmons reagent,HWE amino acid synthesis reagent,Dehydroamino acid precursor,Unnatural amino acid building block,Asymmetric hydrogenation substrate,Pharmaceutical grade N-Cbz-2-Phosphonoglycine trimethyl ester,Peptide modification intermediate,Targeted oncology API building block,Antiviral drug intermediate,Peptidomimetic raw material,Chiral pharmaceutical intermediate,Agrochemical synthesis building block,Fine organic chemical reagent,High purity N-Cbz-2-Phosphonoglycine trimethyl ester 99%,N-Cbz-2-Phosphonoglycine trimethyl ester manufacturer China,CAS 88568-95-0 supplier,Suzhou Health Chemicals phosphonates,Trimethyl N-(benzyloxycarbonyl)-2-phosphonoglycinate wholesale bulk export

 

N-Cbz-2-Phosphonoglycine trimethyl ester serves as an indispensable organophosphorus synthon, premier Horner-Wadsworth-Emmons (HWE) amino acid reagent, and versatile chiral pharmaceutical intermediate extensively utilized across medicinal chemistry, therapeutic peptide engineering, asymmetric catalytic hydrogenation, sustainable agrochemicals, and fine organic synthesis sectors. In active pharmaceutical ingredient (API) manufacturing and unnatural amino acid synthesis, widely recognized as Trimethyl N-(benzyloxycarbonyl)-2-phosphonoglycinate, its stabilized alpha-phosphonate carbanion undergoes smooth, stereoselective Horner-Wadsworth-Emmons condensation with a broad array of aromatic, heterocyclic, and aliphatic aldehydes under mild basic conditions to construct N-Cbz-protected alpha,beta-dehydroamino acid methyl esters in high chemical yields; these versatile unsaturated intermediates subsequently serve as premier prochiral benchmark substrates for transition-metal-catalyzed (rhodium, ruthenium, iridium) homogeneous asymmetric hydrogenation, enabling the commercial-scale enantioselective production of optically pure L- and D-configured non-proteinogenic amino acids, peptidomimetic oncology therapeutics, protease inhibitors, and cardiovascular drug candidates. In peptide chemistry and bioconjugate research, this building block enables the site-specific incorporation of rigid dehydroamino acid residues into therapeutic peptide chains to constrain backbone conformations and dramatically enhance metabolic stability against proteolytic cleavage. In modern crop protection chemistry, it acts as a valuable precursor for assembling bioactive peptidomimetic herbicides, fungicides, and plant defense activators. In advanced biomaterials and polymer engineering, its derivative copolymers are employed in synthesizing biocompatible hydrogels and functional drug-release matrices. Furthermore, in specialty structural adhesives, functional protective coatings, and coordination corrosion inhibitors for petroleum and natural gas infrastructure, chemical architectures derived from N-Cbz-2-Phosphonoglycine trimethyl ester deliver superior chemoselectivity, stereochemical precision, and broad multi-industry performance.