Withanolide A

Product Details

CAS No:32911-62-9

MF:C28H38O6

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:KGS

Synonyms:Withanolide A 32911-62-9;WITHANOLIDE A(P);(20R,22R)-5α,20-Dihydroxy-6α,7α:22,26-diepoxyergosta-2,24-diene-1,26-dione;(22R)-1-Oxo-5,20,22-trihydroxy-6α,7α-epoxy-5α-ergosta-2,24-diene-26-oic acid δ-lactone;(22R)-6α,7α-Epoxy-5,20,22-trihydroxy-1-oxo-5α-ergosta-2,24-dien-26-oic acid δ-lactone;WITHANOLIDE A(SH);5,20alpha-Dihydroxy-6alpha,7alpha-epoxy-1-oxowitha-2,24-dienolide;Withaniol; withanolide A; 32911-62-9; Withanolide A, (+)-; V903234S8G; (1S,2S,4S,5R,10R,11S,14S,15S,18S)-15-[(1R)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxyethyl]-5-hydroxy-10,14-dimethyl-3-oxapentacyclo[9.7.0.02,4.05,10.014,18]octadec-7-en-9-one; DTXSID70461487; (5alpha,6alpha,7alpha,22R)-5,20-Dihydroxy-6,7:22,26-diepoxyergosta-2,24-diene-1,26-dione; (1S,2S,4S,5R,10R,11S,14S,15S,18S)-15-((1R)-1-((2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl)-1-hydroxyethyl)-5-hydroxy-10,14-dimethyl-3-oxapentacyclo(9.7.0.02,4.05,10.014,18)octadec-7-en-9-one; RefChem:194919; DTXCID00412306; WITHANOLIDE A (CONSTITUENT OF ASHWAGANDHA ROOT); WITHANOLIDE A(P); UNII-V903234S8G; 15-[1-(4,5-dimethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-1-hydroxyethyl]-5-hydroxy-10,14-dimethyl-3-oxapentacyclo[9.7.0.0^{2,4}.0^{5,10}.0^{14,18}]octadec-7-en-9-one; MFCD07779143; CHEMBL445041; orb1218159; orb1297175; orb3140650; WITHANOLIDE A [USP-RS]; SCHEMBL24804131; CHEBI:175683; DXWHOKCXBGLTMQ-SFQAJKIESA-N; GLXC-14916; Withanolide A, analytical standard; HY-N7028; Withanolide A, >=95% (HPLC); LMST01160019; TN2309; AKOS040760756; EBC-615353; DA-59138; MS-28704; XW164988; CS-0068468; E87198; Q27291676; Withanolide A, United States Pharmacopeia (USP) Reference Standard; (22R)-5,20-Dihydroxy-5alpha,6alpha-6,7:22,26-diepoxyergosta-2,24-diene-1,26-dione; (1S,2S,4S,5R,10R,11S,14S,15S,18S)-15-[(1R)-1-[(2R)-4,5-dimethyl-6-oxo-2,3-dihydropyran-2-yl]-1-hydroxy-ethyl]-5-hydroxy-10,14-dimethyl-3-oxapentacyclo[9.7.0.02,4.05,10.014,18]octadec-7-en-9-one; (1S,2S,4S,5R,10R,11S,14S,15S,18S)-15-[(1R)-1-[(2R)-4,5-dimethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl]-1-hydroxyethyl]-5-hydroxy-10,14-dimethyl-3-oxapentacyclo[9.7.0.0^{2,4}.0^{5,10}.0^{14,18}]octadec-7-en-9-one; (4aR,4bS,6aS,7S,9aS,9bS,9cS,10aS,10bR)-7-((R)-1-((R)-4,5-Dimethyl-6-oxo-3,6-dihydro-2H-pyran-2-yl)-1-hydroxyethyl)-10b-hydroxy-4a,6a-dimethyl-1,4a,4b,5,6,6a,7,8,9,9a,9b,9c,10a,10b-tetradecahydro-4H-cyclopenta[1,2]phenanthro[9,10-b]oxiren-4-one; (5.ALPHA.,6.ALPHA.,7.ALPHA.,22R)-5,20-DIHYDROXY-6,7:22,26-DIEPOXYERGOSTA-2,24-DIENE-1,26-DIONE; 15-[1-(4,5-Dimethyl-6-oxo-2,3-dihydropyran-2-yl)-1-hydroxyethyl]-5-hydroxy-10,14-dimethyl-3-oxapentacyclo[9.7.0.02,4.05,10.014,18]octadec-7-en-9-one

Product application:Withanolide A,32911-62-9,Withanolide-A,Ashwagandha active monomer,Withania somnifera extract isolate,Ergostane steroid lactone,Natural adaptogen ingredient,Neurite outgrowth promoter,BDNF inducer compound,Neuroprotective reference standard,Alzheimer disease research active,Cognitive enhancement raw material,Cortisol balancing supplement ingredient,Anti-stress dietary supplement bulk,Cosmetic grade Withanolide A,Anti-fatigue skin revitalizer,Mitochondrial antioxidant active,Skin barrier calming active,Phytochemical reference standard,High purity Withanolide A 98%,Withanolide A manufacturer China,CAS 32911-62-9 supplier,Suzhou Health Chemicals natural botanical extracts,Withanolide A wholesale bulk export

 

Withanolide A serves as an indispensable, ultra-pure phytochemical building block, premier natural neuroprotective therapeutic lead, and versatile biological adaptogen extensively utilized across neuropharmacology, cognitive health dietary supplements, restorative cosmeceuticals, and advanced natural product chemistry sectors. In clinical medicinal chemistry and neuroscience discovery, recognized as a flagship bioactive ergostane-type steroidal lactone isolated from Withania somnifera (Ashwagandha), it possesses the distinct capability to traverse the blood-brain barrier to modulate synaptic plasticity; it upregulates brain-derived neurotrophic factor (BDNF) signaling cascades and stimulates significant axonal and dendritic regeneration in cortical and hippocampal neurons, demonstrating profound therapeutic potential in reconstructing damaged neuronal networks impaired by beta-amyloid aggregates, excitotoxicity, and oxidative stress, thereby serving as a vital active pharmaceutical ingredient (API) lead compound for Alzheimer's disease, Parkinson's pathology, depressive cognitive dysfunction, and ischemic brain injury. In modern dietary supplementation and functional food science, it operates as a potent natural adaptogenic active that normalizes hyperactive hypothalamic-pituitary-adrenal (HPA) axis signaling, downregulates elevated baseline serum cortisol levels, and counteracts physical and psychological exhaustion, making it an essential active compound in premium nootropic capsules, stress-relief drink mixes, and sleep-architecture enhancers. In advanced skincare and cosmetic chemistry, it functions as a neuro-cosmetic anti-stress active that protects the cutaneous barrier against cortisol-mediated tissue thinning, enhances mitochondrial vitality in dermal fibroblasts, and scavenges cellular reactive oxygen species, delivering visible firming and revitalizing results in anti-fatigue creams and barrier-calming facial serums. Furthermore, in neural cell differentiation protocols, neurobiological receptor binding assays, and analytical standardization of botanical pharmaceuticals, Withanolide A delivers outstanding stereochemical purity, biological safety, and broad multi-industry performance.