Cinchonine

Product Details

CAS No:118-10-5

MF:C19H22N2O

Appearance:white or light-yellow crystalline powder

Specification:98.5%

UN number:UN 1544 6.1/PG III

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:(8r,9s)-cinchonine;(9s)-cinchonan-9-o;(9S)-Cinchonan-9-ol;D-CINCHONINE;CINCHONINE;CINCHONAN-9-OL,(9S)-;Cinchonine, 98+%;Cinchonine dihydrate monohydrochloride,Cinchonine,"cinchonine; 118-10-5; D-Cinchonine; Cinchonan-9-ol, (9S)-; (9S)-Cinchonan-9-ol; (8R,9S)-Cinchonine; (+)-Cinconine; NSC-6176; V43X79NZCD; DTXSID6045082; CHEBI:27509; DTXCID801474963; 2-Quinuclidinemethanol, alpha-(5-vinyl-2-quinolyl)-; alpha-(5-Vinyl-2-quinuclidinyl)-4-quinolinemethanol; (S)-[(2R,4S,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-quinolin-4-ylmethanol; (S)-((2R,4S,5R)-5-ethenyl-1-azabicyclo(2.2.2)octan-2-yl)-quinolin-4-ylmethanol; LA-40221; 204-234-6; (+)-Cinchonine; MFCD00064372; (1S)-Quinolin-4-yl((2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol; (+)-cinchonin; (S)-Quinolin-4-yl((1S,2R,4S,5S)-5-vinylquinuclidin-2-yl)methanol; cinchonin; 2-Quinuclidinemethanol, .alpha.-(5-vinyl-2-quinolyl)-; NSC6176; .alpha.-Quinidine; (S)-4-quinolyl-[(2R,4S,5R)-5-vinylquinuclidin-2-yl]methanol; (S)-Quinolin-4-yl-(5-vinyl-1-aza-bicyclo[2.2.2]oct-2-yl)-methanol; UNII-V43X79NZCD; (S)-quinolin-4-yl((1S,2R,4S,5R)-5-vinylquinuclidin-2-yl)methanol; (9S)-Cinchonan-9-ol; Cinchonine (8CI); (+)-Cinchonine; (8R,9S)-Cinchonine; NSC 6176; d-Cinchonine; CAS-118-10-5; NSC 6176; EINECS 204-234-6; CINCHORINE; Cinchonine (Standard); CINCHONINE [MI]; AI3-09058; Prestwick3_000608; 2-Quinuclidinemethanol, .alpha.-4-quinolyl-5-vinyl-; (+)-Cinchonine, 85%; CINCHONINE [WHO-DD]; (+)-Cinchonine; 99%; BSPBio_000516; MLS002153907; SCHEMBL158394; SCHEMBL158395; BPBio1_000568; CHEMBL588619; MEGxp0_001905; orb1311022; SCHEMBL29364855; ACon0_001352; ACon1_000336; GTPL13363; HY-Y0152R; HMS2096J18; HMS2235N18; HY-Y0152; Tox21_110009; (+)-Cinchonine, analytical standard; BDBM50370411; MSK159057; AKOS015895982; FC11047; NCGC00013067-01; NCGC00169174-01; NCGC00169174-02; NCGC00262542-03; NCGC00262542-10; DS-15267; NCI60_005298; SMR001233256; Cinchonine, crystallized, 98.0% (NT); AB00374715; CS-0008420; O10016; WLN: T66 BNJ EYQ-DT66 A B CNTJ A1U1; AL-466/21162039; AM-331/20711019; Q2972710; BRD-K90268819-001-03-4; 4-Quinolyl(5-vinyl-1-azabicyclo[2.2.2]oct-2-yl)methanol;(5-Ethenyl-1-azabicyclo[2.2.2]oct-2-yl)(quinolin-4-yl)methanol",294.400,C19H22N2O,

Product application:Cinchonine, 118-10-5, (+)-Cinchonine, Cinchonan-9-ol, Suzhou Health Chemicals Co. Ltd., Chiral Resolving Agent, Asymmetric Organocatalyst, Cinchona Alkaloids, Chiral Ligand, Quinuclidine Derivative, Pharmaceutical Intermediate, Anti-malarial Precursor, High Purity Cinchonine, Cinchonine Supplier China, Cinchonine Manufacturer, Chiral Phase Transfer Catalyst, Racemic Acid Resolution, Chemical Reagent CAS 118-10-5, Cinchonine Factory Price, Cinchonine Exporter

 

Cinchonine (CAS: 118-10-5) is a vital natural cinchona alkaloid featuring a rigid polycyclic quinuclidine-quinoline skeleton, widely utilized across chemical, pharmaceutical, and industrial sectors. In asymmetric organic synthesis, cinchonine and its quaternary ammonium or thiourea derivatives function as highly effective chiral organocatalysts and chiral phase-transfer catalysts for enantioselective transformations including Michael additions, Aldol reactions, Henry reactions, and asymmetric fluorinations. In industrial chiral optical resolution, cinchonine serves as a premier basic resolving agent to separate racemic organic acids, amino acid derivatives, and pharmaceutical intermediates via diastereomeric salt crystallization. Within pharmaceutical R&D and manufacturing, it acts as a essential synthetic precursor and building block for antimalarial agents, antiparasitic formulations, and cancer chemotherapy multidrug-resistance (MDR) reversing candidates. Additionally, in metallurgy and surface finishing, cinchonine is applied as a metal pickling corrosion inhibitor and a brightening or grain-refining additive in electroplating baths for metals like bismuth and cadmium, as well as a analytical reagent for photometrically determining heavy metals.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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