Methyl (2S)-2-aminobutanoate Hydrochloride

Product Details

CAS No:56545-22-3

MF:C5H11NO2.HCl

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:(S)-2-AMinobutanoic Acid Methyl Ester Hydrochloride;(S)-2-AMino-butanoic Acid Methyl Ester Hydrochloride;L-α-AMinobutyric Acid Methyl Ester Hydrochloride;Methyl (2S)-2-aminobutanoate hydrochloride;Methyl L-2-aminobutanoate hydrochloride;Methyl (S)-2-aMinobutanoate HCl;L-2-Amino butanoic acid methyl ester hydrochloride;L-2-AMINOBUTYRIC ACID METHYL ESTER HCL; (S)-Methyl 2-aminobutanoate hydrochloride; RefChem:408148; 820-188-5; 56545-22-3; methyl (2S)-2-aminobutanoate hydrochloride; H-ABU-OME HCL; MFCD09037399; L-2-Aminobutyric Acid Methyl Ester Hydrochloride; methyl (2S)-2-aminobutanoate;hydrochloride; SCHEMBL1064128; methyl (s)-aminobutyrate hydrochloride; (S)-Methyl2-aminobutanoatehydrochloride; methyl (s)-2-aminobutyrate hydrochloride; DS-12386; CS-0031391; F11947; Methyl (S)-2-aminobutanoate HCl; (S)-2-Amino-butanoic Acid Methyl Ester Hydrochloride; L-alpha-Aminobutyric Acid Methyl Ester Hydrochloride; (S)-2-Aminobutanoic Acid Methyl Ester Hydrochloride;; L-2-Abu-Ome.HCl; H-Abu-OMe inverted exclamation mark currencyHCl; Methyl L-homoalaninate HCl; DTXSID40746990; Butanoic acid, 2-amino-, methyl ester, hydrochloride, (2S)-; Methyl L-homoalaninate hydrochloride; AKOS027250613; methyl (S)-aminobutanoate hydrochloride; SY096587; EN300-395958; F500445; Methyl (2S)-2-aminobutanoate--hydrogen chloride (1/1); 56545-22-3?5399-22-1ree base?Levetiracetam Impurity 19

Product application:Methyl (2S)-2-aminobutanoate Hydrochloride,56545-22-3,L-2-Aminobutyric acid methyl ester hydrochloride,H-Abu-OMe.HCl,L-alpha-Aminobutyrate methyl ester hydrochloride,Methyl (S)-2-aminobutanoate hydrochloride,Pharmaceutical grade methyl (2S)-2-aminobutanoate hydrochloride,Levetiracetam intermediate,Brivaracetam intermediate,Antiepileptic drug building block,Chiral amino acid ester,Unnatural amino acid derivative,Peptide synthesis building block,Antiviral protease inhibitor synthon,Agrochemical intermediate,Imidazolinone herbicide precursor,Chiral ligand precursor,High enantiomeric purity intermediate,High purity Methyl (2S)-2-aminobutanoate Hydrochloride 99.5%,CAS 56545-22-3 supplier,Methyl (2S)-2-aminobutanoate Hydrochloride manufacturer China,Suzhou Health Chemicals specialty chemicals,L-2-Aminobutyric acid methyl ester hydrochloride wholesale bulk export

 

Methyl (2S)-2-aminobutanoate Hydrochloride serves as an indispensable, ultra-pure chiral amino acid ester intermediate, benchmark central nervous system active pharmaceutical ingredient (API) building block, and versatile fine organic synthon extensively utilized across modern antiepileptic drug manufacturing, antiviral peptidomimetic synthesis, high-selectivity chiral agrochemical discovery, and asymmetric catalysis sectors. In medicinal chemistry and process pharmacology, universally designated as H-Abu-OMe.HCl or L-2-aminobutyric acid methyl ester hydrochloride, its molecular architecture incorporates a rigid (2S)-configured alpha-carbon substituted with an ethyl side chain, an electrophilic methyl ester group, and a protonated primary amine hydrochloride salt; stabilizing the primary amine as a stoichiometric hydrochloride salt effectively prevents intermolecular self-condensation into unwanted diketopiperazine impurities, delivering thermodynamic crystalline stability alongside instant cold-water solubility; upon base-induced liberation of the active nucleophilic primary amine under mild reaction conditions, it undergoes smooth regioselective acylation and subsequent intramolecular cyclization with substituted butyryl halides to generate chiral 2-pyrrolidone heterocyclic rings with high enantiomeric retention; this precise S-enantiomeric spatial architecture provides the critical pharmacophore responsible for selective binding affinity toward synaptic vesicle protein 2A (SV2A) in blockbuster antiepileptic therapeutics, most notably levetiracetam and next-generation brivaracetam, enabling effective suppression of epileptic hypersynchronous neuronal discharge with favorable oral bioavailability and minimal neurocognitive impairment; in antiviral medicinal chemistry and peptidomimetic development, the unnatural ethyl side chain acts as a steric modifier replacing natural aliphatic amino acids, enhancing resistance against proteolytic degradation by host peptidases to prolong systemic circulatory half-life; in sustainable crop protection chemistry, it functions as an essential chiral precursor for constructing low-application-rate imidazolinone herbicides and insecticidal heterocyclic pharmacophores. Furthermore, in chiral oxazoline ligand engineering, asymmetric organocatalyst assembly, and specialized biochemical probe functionalization, chemical systems engineered from Methyl (2S)-2-aminobutanoate Hydrochloride deliver exceptional stereochemical fidelity, reliable reaction kinetics, and broad multi-industry performance.