Triphenylmethyl chloride

Product Details

CAS No:76-83-5

MF:C19H15Cl

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:UN 3261 8/PG III

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:1,1’,1’’-(chloromethylidyne)tris-benzen;1,1’,1’’(-Chloromethylidyne)trisben-zene;chlorotriphenyl-methan;Methane, chlorotriphenyl-;BENZENE, 1,1',1''-(CHLOROMETHYLIDYNE)TRIS-;TRITY CHLORIDE;TRIPHENYLMETHYL CHLORIDE;TRIPHENYLCHLORMETHANE; Trityl chloride; 76-83-5; Triphenylchloromethane; CHLOROTRIPHENYLMETHANE; Methane, chlorotriphenyl-; triphenylmethylchloride; Benzene, 1,1',1''-(chloromethylidyne)tris-; DTXSID3052511; 1,1',1''-(Chloromethylidyne)trisbenzene; 1D9GZ8QQXN; NSC-435; DTXCID7031084; RefChem:575983; 200-986-4; Triphenylmethyl chloride; (chloromethanetriyl)tribenzene; (chlorodiphenylmethyl)benzene; Trityl Chloride Resin; [Chloro(diphenyl)methyl]benzene; C19H15Cl; 1411984-26-3; 1,1',1''-(chloromethanetriyl)tribenzene; MFCD00284810; triphenyl chloromethane; HSDB 2807; NSC 435; Olmesartan Impurity 29; EINECS 200-986-4; UNII-1D9GZ8QQXN; Chlorotriphenylmethane resin; BRN 0397363; tritylchloride; trityl-chloride; AI3-51298; TrtCl; trt-cl; TrCl; Cl-Trt; Ph3CCl; triphenymethylchloride; MFCD00000813; TPCM; chloro triphenylmethane; triphenylmethyl choride; 3880-98-6; Chlorotriphenyl methane; Chlorotriphenyl-methane; triphenylmethyl-chloride; Trityl chloride, 97%; triphenyl methyl chloride; triphenyl-methyl chloride; triphenyl-methyl-chloride; (triphenyl)methyl chloride; SCHEMBL461; diphenyl-phenyl-chloromethane; SCHEMBL82940; TRITYL CHLORIDE [MI]; 4-05-00-02497 (Beilstein Handbook Reference); (chloro-diphenyl-methyl)benzene; CHEMBL261393; NSC435; orb1306629; orb1940507; SCHEMBL2599011; SCHEMBL16781670; BDBM23782; [Chloro(diphenyl)methyl]benzene #; STR01707; Tox21_303949; c0308; SBB058862; STK366821; AKOS005444080; Triphenylchloromethane; Trityl chloride; CS-W009020; FT01757; FT29918; CAS-76-83-5; Triphenylmethyl-containing compound, 11; NCGC00357183-01; BP-21049; Benzene,1',1''-(chloromethylidyne)tris-; 1,1',1''-(chloromethylidyne)tris-benzene; Benzene, 1,1',1"-(chloromethylidyne)tris-; NS00037847; ST50893796; EN300-21614; C93509; M02871; T-7290; T20519; Benzene, 1,1',1''-(chloromethylidyne-13C)tris-; Q2790082; F0001-1923; Trityl chloride, purum, >=97.0% (HPLC), >=97.0% (AT); Trityl chloride resin (100-200 mesh, 1% DVB, 1.2-2.0 mmol/g; Trityl chloride resin (200-400 mesh, 1% DVB, 1.2-2.0 mmol/g); InChI=1/C19H15Cl/c20-19(16-10-4-1-5-11-16,17-12-6-2-7-13-17)18-14-8-3-9-15-18/h1-15

Product application:Triphenylmethyl chloride,76-83-5,Trityl chloride,Chlorotriphenylmethane,Triphenylchloromethane,Tr-Cl,Trityl protecting reagent,Hydroxyl protecting group,Amino protecting reagent,Thiol protecting agent,Peptide synthesis reagent,Nucleoside drug intermediate,Antiviral API raw material,Oligonucleotide synthesis building block,Triphenylmethyl radical precursor,Triarylmethane dye intermediate,Cationic polymerization initiator,Hydride transfer reagent,Polymer chain terminator,Photosensitive resin modifier,Fine organic chemical intermediate,High purity Triphenylmethyl chloride 99.5%,Triphenylmethyl chloride manufacturer China,CAS 76-83-5 supplier,Suzhou Health Chemicals specialty chemicals,Trityl chloride wholesale bulk export

 

Triphenylmethyl chloride serves as an indispensable, high-purity sterically hindered protecting reagent, versatile synthetic intermediate, and specialized chemical building block extensively utilized across antiviral pharmaceutical manufacturing, oligonucleotide therapeutics, solid-phase peptide synthesis, specialty functional dyes, and advanced materials engineering sectors. In active pharmaceutical ingredient (API) manufacturing and nucleic acid biopharmaceuticals, universally designated as Trityl chloride or Tr-Cl, its bulky triaryl core imparts exceptional regioselectivity, allowing it to selectively functionalize primary hydroxyls over secondary hydroxyls, as well as unprotected primary amines and cysteine sulfhydryl groups under mild basic conditions to form robust trityl ethers, amines, or thioethers; these protective adducts withstand aggressive alkaline, organometallic, and coupling conditions while remaining cleanly cleavable under mild acidic or catalytic hydrogenolytic environments, making it a gold-standard reagent for commercial multi-step synthesis of nucleoside antiviral agents, synthetic oligonucleotide drug platforms, cyclic peptide therapeutics, and complex carbohydrate conjugates. In synthetic organic chemistry and homogeneous catalysis, it functions as a primary chemical precursor for generating persistent triphenylmethyl free radicals, trityl carbocations, and trityl tetrafluoroborate salts utilized as hydride-abstracting agents in catalytic oxidative transformations and asymmetric syntheses. In dye manufacturing and specialty colorants, it serves as a central structural backbone for synthesizing triarylmethane dyes, advanced optical markers, and chromogenic leuco-colorants for thermal recording media. In polymer engineering and rubber-plastic processing, it is deployed as an effective chain terminator in living ionic polymerizations, a cationic polymerization initiator component, and a thermal oxidation stabilizer for elastomeric vulcanizates. In functional adhesives, automotive protective topcoats, and semiconductor photolithography, its derivatives assist in formulating photoacid generator systems and light-sensitive resist polymers. Furthermore, in functional textile finishing auxiliaries, leather protective coatings, wood adhesive resins, and specialized anti-corrosion additives for petroleum and natural gas pipelines, molecular architectures derived from Triphenylmethyl chloride deliver superior steric shielding, chemical stability, and multi-industry versatility.