SKQ-1 Bromide; Visomitin

Specifications:

Item

Standards

Appearance:

White or light-yellow solid

Odor:

Characteristic

Identification:

IR/HPLC/Mass/NMR Spectrum

Purity: (HPLC)

≥95.0%

Applications:

Mitochondrial antioxidant SKQ-1 Bromide.

SKQ-1 Bromide is a new type of mitochondrial antioxidant with the highest mitochondrial penetration and effective antioxidant capacity. SKQ-1 is added to cosmetics as an antioxidant; SKQ-1 Bromide is added to eye drops as an ingredient to prevent dry eyes.

SKQ-1 Bromide is an antioxidant with effective antioxidant capacity, used to reduce oxidative stress damage to tissues and cells. Key applications include: research and application in anti-aging, improving skin function, and wound healing. It is used as an antioxidant additive in cosmetics. In the pharmaceutical field, it shows promise for treating inflammation related to ocular surface diseases such as Dry Eye Disease (DED) and corneal wounds, and as an ingredient in eye drops to prevent dry eyes. Research suggests it protects against acute kidney injury by reducing inflammation, lowering oxidative stress, and maintaining normal mitochondrial morphology.

SKQ-1 Bromide (Visomitin) is a highly bioactive mitochondrial-targeting antioxidant, holding a leading position in biochemical and pharmacological research. Its molecular structure consists of a proton-permeable cationic triphenylphosphine moiety linked to an antioxidant plastoquinone moiety via a long fatty acid chain. This unique structure endows SKQ-1 Bromide (Visomitin) with extremely strong lipophilicity, enabling it to cross cell membranes and accumulate precisely in the inner mitochondrial membrane. At micromolar or even nanometer-scale concentrations, SKQ-1 Bromide (Visomitin) effectively scavenges reactive oxygen species (ROS) produced by mitochondria, blocking cell damage caused by oxidative stress at its source. Due to its excellent biostability and precise targeting, it has become an important candidate molecule for research on delaying aging, treating retinal degeneration, and various mitochondrial-related diseases.

1: SKQ-1 Bromide (Visomitin) is widely used in the ophthalmic pharmaceutical industry for the development of drugs for dry eye and retinal damage. 1. Due to its ability to deeply penetrate eye tissue and target mitochondria, this product significantly alleviates oxidative stress in eye tissues, protects conjunctival epithelial cells, and improves tear secretion quality, making it a key active ingredient in the development of highly effective ophthalmic drugs.

2. SKQ-1 Bromide (Visomitin) is used as a core functional reagent in biomedical anti-aging research. It can slow down the systemic aging process at the cellular level by reducing free radical levels in mitochondria, decreasing the rate of telomere shortening, and maintaining mitochondrial membrane potential. It is commonly used in longevity science and experimental models for delaying cellular aging.

3. SKQ-1 Bromide (Visomitin) has shown significant application value in the field of neurodegenerative disease research. In studies targeting Alzheimer's disease, Parkinson's disease, and other models, it can protect neurons from oxidative-induced apoptosis and enhance the stress resistance of nerve cells, providing important data support for the development of novel neurotrophic drugs.

4. SKQ-1 Bromide (Visomitin) plays a crucial cytoprotective role in cardiovascular disease research. By targeting mitochondria, it can reduce oxidative damage during myocardial ischemia-reperfusion and decrease the necrosis rate of cardiomyocytes, playing an irreplaceable role in the screening of drugs for strengthening cardiac function and protecting the circulatory system.

5: SKQ-1 Bromide (Visomitin) has been used as a benchmark for high-efficiency antioxidants in efficacy tests of cosmetics and high-end skin care ingredients. Its powerful reactive oxygen species scavenging ability can effectively neutralize free radicals generated by ultraviolet radiation (UV) and environmental pollution, protecting dermal fibroblasts and preventing collagen degradation and photoaging of the skin.

Package: 1/10/100g per bottle

UN number: Not dangerous goods

Store at: Sealed storage in a cool and dry place at 0℃, avoid light and heat.

Shelf Life: Two years