2,2-Dimethyl-1,3-dioxane-4,6-dione

Product Details

CAS No:2033-24-1

MF:C6H8O4

Appearance:white or off-white to beige-brown crystalline powder

Specification:99.0%

UN number:-

Package:25kg/drum

Supply Capacity:Tons

Product application:Meldrum's Acid, 2,2-Dimethyl-1,3-dioxane-4,6-dione, CAS 2033-24-1, Isopropylidene malonate, High purity Meldrum's Acid, White crystalline powder, Active methylene compound, Organic synthesis intermediate, Pharmaceutical intermediate, Agrochemical intermediate, Knoevenagel condensation reagent, Acylation reagent, Synthesis of heterocycles, Meldrum's Acid derivatives, Meldrum's Acid manufacturer, Industrial grade Meldrum's acid, Laboratory chemical, Meldrum's acid solubility, Chemical properties of Meldrum's acid, Malonic acid derivative.

Synonyms:MELDRUMS ACID;'MELDRUM'S ACID';MELDRUM'S ACID;MALONIC ACID CYCLIC ISOPROPYLIDENE ESTER;LABOTEST-BB LT00233174;Isopropyl Malonate;Meldrum’s acid, Malonic acid cyclic isopropylidene ester;2,2-DiMethyl-1,3-dioxane-4,6-dione, 98% 25GR,"2,2-Dimethyl-1,3-dioxane-4,6-dione","2,2-Dimethyl-1,3-dioxane-4,6-dione; 2033-24-1; Meldrum's acid; 1,3-Dioxane-4,6-dione, 2,2-dimethyl-; Isopropylidene malonate; Cyclic isopropylidene malonate; Malonic acid, cyclic isopropylidene ester; 2,2-Dimethyl-m-dioxane-4,6-dione; DD139RP1SC; NSC-71902; NSC-688343; DTXSID7051846; DTXCID5030402; 217-992-8; 2,2-Dimethyl-1,3-dioxan-4,6-dione; Meldrums acid; MFCD00006638; Malonic acid cyclic isopropylidene ester; cycl-Isopropylidene malonate; 2,2-Dimethyl-4,6-dioxo-m-dioxane; NSC 71902; AI3-39039; m-DIOXANE-4,6-DIONE, 2,2-DIMETHYL-; 2,2-dimethyl-4,6-dioxo-1,3-dioxane; 2,2-dimethyl-[1,3]dioxane-4,6-dione; NSC688343; MELDRUMIC ACID; MELDRUM ACID; EINECS 217-992-8; UNII-DD139RP1SC; BRN 0117310; Meidrum's Acid; Meldrum\\'s acid; 2,6-dione; 2,2-PROPANEDIOL CYCLIC MALONATE; 2,6-dioxo-m-dioxane; EC 217-992-8; SCHEMBL5976; MELDRUM'S ACID [MI]; 5-19-05-00008 (Beilstein Handbook Reference); 1,6-dione, 2,2-dimethyl-; orb1306435; SCHEMBL5281483; SCHEMBL5964898; m-Dioxane-4, 2,2-dimethyl-; N,N-Dimethyl-1-4-aminobilidine; ALBB-013484; CS-D1154; Dimethyl-[1,3]dioxane-4,6-dione; HY-Y0232; NSC71902; STR00259; CX1199; SBB071729; STK397458; 2,2-dimethyl-1,3-dioxane-4,6dione; 2,2-dimethyl-1,3-dioxane4,6-dione; 2,2dimethyl-1,3-dioxane-4,6-dione; AKOS000119035; AB00787; AC-2044; FC04271; 2,2 dimethyl-1,3 dioxane-4,6 dione; 2.2-dimethyl-1,3-dioxane-4,6-dione; 4,6-Diketo-2,2-dimethyl-1,3-dioxane; 2.2-dimethyl-[1,3]dioxane-4,6-dione; SY001708; 2, 2-dimethyl-1,3-dioxane-4, 6-dione; 2,2-dimethyl-[1,3]-dioxan-4,6-dione; 2,2-dimethyl-[1,3]-dioxane-4,6-dione; M0799; NS00005683; ST45026906; EN300-19266; 2,2-Dimethyl-1,3-dioxane-4,6-dione, 98%; Q421283; 2,2-Dimethyl-1,3-dioxane-4,6-dione;Meldrum's acid; F3096-1700; InChI=1/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H; Malonic acid cyclic isopropylidene ester, Meldrum's acid, cycl-Isopropylidene malonate",144.120,C6H8O4,

 

Applications:
Meldrum's Acid, chemically known as 2,2-Dimethyl-1,3-dioxane-4,6-dione, is an indispensable reagent in modern organic synthesis. Due to its rigid cyclic structure and unusually high acidity, it serves as a more reactive and versatile alternative to malonic esters.

 

1.    Pharmaceutical Synthesis: A key intermediate for manufacturing cardiovascular drugs, antibiotics, and barbiturates. It is essential for the synthesis of diverse non-natural amino acids.
2.    Knoevenagel Condensation: Reacts efficiently with aldehydes even in the absence of strong bases, providing a streamlined route to fine chemical intermediates.
3.    Heterocyclic Construction: The ketenes generated from Meldrum’s acid are widely used to build pyrroles, indoles, and quinolines, which are core structures in agrochemicals and medicines.
4.    Polymer Science: Utilized as a functional monomer for the cross-linking of high-performance polymers or as a thermal-latent acid catalyst.
5.    Flavors & Photo-sensitive Materials: Serves as a fundamental building block in the synthesis of fragrances and as a modifier for specialized photoresists.