2,2-Dimethyl-1,3-dioxane-4,6-dione

Product Details

CAS No:2033-24-1

MF:C6H8O4

Appearance:white or off-white to beige-brown crystalline powder

Specification:99.0%

Package:25kg/drum

Supply Capacity:Tons

Synonyms:2,2-Dimethyl-1,3-dioxane-4,6-dione; Malonic acid cyclic isopropylidene ester; Meldrum's acid; MELDRUMS ACID;'MELDRUM'S ACID';MELDRUM'S ACID;MALONIC ACID CYCLIC ISOPROPYLIDENE ESTER;LABOTEST-BB LT00233174;Isopropyl Malonate;Meldrum’s acid, Malonic acid cyclic isopropylidene ester;2,2-DiMethyl-1,3-dioxane-4,6-dione, 98% 25GR; 2,2-Dimethyl-1,3-dioxane-4,6-dione","2,2-Dimethyl-1,3-dioxane-4,6-dione; 2033-24-1; Meldrum's acid; 1,3-Dioxane-4,6-dione, 2,2-dimethyl-; Isopropylidene malonate; Cyclic isopropylidene malonate; Malonic acid, cyclic isopropylidene ester; 2,2-Dimethyl-m-dioxane-4,6-dione; DD139RP1SC; NSC-71902; NSC-688343; DTXSID7051846; DTXCID5030402; 217-992-8; 2,2-Dimethyl-1,3-dioxan-4,6-dione; Meldrums acid; MFCD00006638; Malonic acid cyclic isopropylidene ester; cycl-Isopropylidene malonate; 2,2-Dimethyl-4,6-dioxo-m-dioxane; NSC 71902; AI3-39039; m-DIOXANE-4,6-DIONE, 2,2-DIMETHYL-; 2,2-dimethyl-4,6-dioxo-1,3-dioxane; 2,2-dimethyl-[1,3]dioxane-4,6-dione; NSC688343; MELDRUMIC ACID; MELDRUM ACID; EINECS 217-992-8; UNII-DD139RP1SC; BRN 0117310; Meidrum's Acid; Meldrum\\'s acid; 2,6-dione; 2,2-PROPANEDIOL CYCLIC MALONATE; 2,6-dioxo-m-dioxane; EC 217-992-8; SCHEMBL5976; MELDRUM'S ACID [MI]; 5-19-05-00008 (Beilstein Handbook Reference); 1,6-dione, 2,2-dimethyl-; orb1306435; SCHEMBL5281483; SCHEMBL5964898; m-Dioxane-4, 2,2-dimethyl-; N,N-Dimethyl-1-4-aminobilidine; ALBB-013484; CS-D1154; Dimethyl-[1,3]dioxane-4,6-dione; HY-Y0232; NSC71902; STR00259; CX1199; SBB071729; STK397458; 2,2-dimethyl-1,3-dioxane-4,6dione; 2,2-dimethyl-1,3-dioxane4,6-dione; 2,2dimethyl-1,3-dioxane-4,6-dione; AKOS000119035; AB00787; AC-2044; FC04271; 2,2 dimethyl-1,3 dioxane-4,6 dione; 2.2-dimethyl-1,3-dioxane-4,6-dione; 4,6-Diketo-2,2-dimethyl-1,3-dioxane; 2.2-dimethyl-[1,3]dioxane-4,6-dione; SY001708; 2, 2-dimethyl-1,3-dioxane-4, 6-dione; 2,2-dimethyl-[1,3]-dioxan-4,6-dione; 2,2-dimethyl-[1,3]-dioxane-4,6-dione; M0799; NS00005683; ST45026906; EN300-19266; 2,2-Dimethyl-1,3-dioxane-4,6-dione, 98%; Q421283; 2,2-Dimethyl-1,3-dioxane-4,6-dione;Meldrum's acid; F3096-1700; InChI=1/C6H8O4/c1-6(2)9-4(7)3-5(8)10-6/h3H2,1-2H; Malonic acid cyclic isopropylidene ester, Meldrum's acid, cycl-Isopropylidene malonate",144.120,C6H8O4,;

Applications:
Meldrum's Acid, chemically known as 2,2-Dimethyl-1,3-dioxane-4,6-dione, is an indispensable reagent in modern organic synthesis. Due to its rigid cyclic structure and unusually high acidity, it serves as a more reactive and versatile alternative to malonic esters.

1.    Pharmaceutical Synthesis: A key intermediate for manufacturing cardiovascular drugs, antibiotics, and barbiturates. It is essential for the synthesis of diverse non-natural amino acids.
2.    Knoevenagel Condensation: Reacts efficiently with aldehydes even in the absence of strong bases, providing a streamlined route to fine chemical intermediates.
3.    Heterocyclic Construction: The ketenes generated from Meldrum’s acid are widely used to build pyrroles, indoles, and quinolines, which are core structures in agrochemicals and medicines.
4.    Polymer Science: Utilized as a functional monomer for the cross-linking of high-performance polymers or as a thermal-latent acid catalyst.
5.    Flavors & Photo-sensitive Materials: Serves as a fundamental building block in the synthesis of fragrances and as a modifier for specialized photoresists.