4-Aminobenzonitrile

Product Details

CAS No:873-74-5

MF:C7H6N2

Appearance:off-white or light-yellow to yellow crystalline powder

Specification:99.0%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:4-CyanobenzenaMine;4-CyanobenzeneaMine;4-CyanophenylaMine;NSC 7625;p-CyanophenylaMine;4-AMinobenonitrile;4-AMINOBENZONITRILE FOR SYNTHESIS;TheaMinobenzonitrile; 4-Aminobenzonitrile; 873-74-5; 4-Cyanoaniline; P-AMINOBENZONITRILE; p-Cyanoaniline; Benzonitrile, 4-amino-; Benzonitrile, p-amino-; 1-Amino-4-cyanobenzene; PB8V69Y76T; DTXSID0061240; NSC-7625; para-aminobenzonitrile; RefChem:97838; DTXCID3048578; 212-850-1; Aniline, p-cyano-; MFCD00007821; 4-amino-benzonitrile; p-Cyanophenylamine; 4-aminobezonitrile; 4-Cyanobenzenamine; BRN 0774507; CS-D1531; aniline, 4-cyano-; 4-aminobenzenecarbonitrile; A0695; S12319; 4-aminobenzonitrile-2356-d4; Dabigatran impurity 84; 4-amino benzonitrile; NSC 7625; EINECS 212-850-1; 4-azanylbenzenecarbonitrile; UNII-PB8V69Y76T; p-cyanoaniIine; AI3-24185; 4-cyanoanilin; 4-cyano aniline; 4-Cyanophenylamine; (2E)-N-[3-(Methylamino)propyl]-3-(thiophen-2-yl)prop-2-enamide Hydrochloride; (E)-N-[3-(Methylamino)propyl]-3-(2-thienyl)-2-propenamide Hydrochloride;; 4-Cyanobenzeneamine; 4-cyano-phenylamine; 4-cyanophenyl amine; p-amino benzonitrile; 4-Aminophenylnitrile; 4-Aminobenzenenitrile; CYANOANILINE, P-; WLN: ZR DCN; 4-DIAZO-N,N-DIETHYLANILINEFLUOROBORATE; 4-Aminobenzonitrile, 98%; SCHEMBL55548; 4-14-00-01158 (Beilstein Handbook Reference); SCHEMBL544424; 4-Cyanoaniline; p-Cyanoaniline; orb3030056; SCHEMBL3886159; SCHEMBL5852751; SCHEMBL27496178; NSC7625; Fr14410; BENZOIC ACID,4-AMINO,NITRILE; SBB008363; STK080905; AKOS000119675; EBC-152139; FA05145; PS-6161; BP-21363; DB-006652; NS00022855; ST45082172; EN300-17909; AC-907/34118024; F024179; Q27286445; Z57073771; F5608-0079

Product application:4-Aminobenzonitrile,873-74-5,4-Cyanoaniline,p-Aminobenzonitrile,p-Cyanoaniline,4-Cyanobenzenamine,4-Aminobenzene-1-carbonitrile,Pharmaceutical grade 4-aminobenzonitrile,Antiviral intermediate,Etravirine intermediate,Rilpivirine key intermediate,Liquid crystal monomer precursor,Azo dye intermediate,NNRTI building block,Aromatic amine nitrile synthon,High purity 4-Aminobenzonitrile 99.5%,Low nitro 4-cyanoaniline,CAS 873-74-5 supplier,4-Aminobenzonitrile manufacturer China,Suzhou Health Chemicals aromatic chemicals,4-Aminobenzonitrile wholesale bulk export

 

4-Aminobenzonitrile is widely utilized across commercial antiviral active pharmaceutical ingredient synthesis, next-generation human immunodeficiency virus (HIV) therapeutic manufacturing, high-resolution liquid crystal display monomer engineering, functional azo dye formulation, and specialty fluorescent probe synthesis sectors. In antiviral medicinal chemistry and process pharmacology, universally recognized across pharmaceutical manufacturing as 4-cyanoaniline or p-aminobenzonitrile, it operates as an indispensable foundational aromatic building block for commercial manufacturing of non-nucleoside reverse transcriptase inhibitors (NNRTIs), including rilpivirine and etravirine; the electronic push-pull interaction between the electron-withdrawing cyano handle and the primary aromatic amino group delivers controlled nucleophilic reactivity, facilitating high-yield aromatic nucleophilic substitution and palladium-catalyzed Buchwald-Hartwig aminations onto functionalized pyrimidine and triazine cores; this transforms the intermediate into the vital p-cyanophenylamino pharmacophore that anchors into the hydrophobic non-nucleoside binding pocket of HIV-1 reverse transcriptase, conferring high therapeutic potency and overcoming clinical mutational resistance profiles; in optoelectronic materials and liquid crystal display technology, the compound serves as an essential terminal precursor for synthesizing cyanobiphenyl and azobenzene mesogens, broadening the nematic temperature operating range and optimizing dielectric anisotropy for high-speed electro-optical switching; furthermore, in specialty color chemistry, 4-Aminobenzonitrile provides dependable diazotization kinetics and robust coupling efficiency across demanding industrial dye and fine chemical manufacturing campaigns.