2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone

Product Details

CAS No:86404-63-9

MF:C10H7F2N3O

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:Triazole Acetophenone;2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone 95%;Imp. E (EP): 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone;2-(1H-1,2,4-Triazol-1-yl)-2',4'-difluoroacetophenone,98%;2,4-DIFLUORO-ALPHA, ALPHA-BIS(1H-1,2,4-T RIAZOL-1YL METHYL)BENZYL ALCOHOL;α-(1H-1,2,4-Triazole-1-yl)-2',4'-difluoroacetophenone;Difluoro triazolyl acetophenone;1-(2,4-diflurorphenyl)-2-(1H-1,2,4-truazol-1-yl) ethanone; 86404-63-9; 1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone; 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone; 2',4'-DIFLUORO-2-(1H-1,2,4-TRIAZOL-1-YL)ACETOPHENONE; Ethanone, 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-; UNII-HXI8R9R915; HXI8R9R915; UK 51060; DTXSID70235529; EC 617-850-9; UK-51060; 1-(2,4-difluorophenyl)-2-(1h-1,2,4-triazol-1-yl)-1-ethanone; FLUCONAZOLE IMPURITY E [EP IMPURITY]; VORICONAZOLE IMPURITY A [EP IMPURITY]; 2',4'-DIFLUORO-2-(1,2,4-TRIAZOL-1-YL)ACETOPHENONE; 2,4-DIFLUORO-.ALPHA.-(1H-1,2,4-TRIAZOLYL)ACETOPHENONE; FLUCONAZOLE IMPURITY E (EP IMPURITY); VORICONAZOLE IMPURITY A (EP IMPURITY); RefChem:73990; DTXCID50158020; UK-51,060; 2',4'-Difluoro-2-(1H-1,2,4-triazol-1-yl)-acetophenone; 617-850-9; XCHRPVARHBCFMJ-UHFFFAOYSA-N; 1-(2,4-difluorophenyl)-2-(1,2,4-triazol-1-yl)ethanone; MFCD02093825; 2-(1H-1,2,4-Triazol-1-yl)-2',4'-difluoroacetophenone; 1-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethan-1-one; 2,4-Difluoro-|A-(1H-1,2,4-triazolyl)acetophenone; F2158-0485; 2,4-Difluoro-a-(1H-1,2,4-triazolyl)acetophenone; Voriconazole EP Impurity A;Fluconazole EP Impurity E; 2',4'-Difluoro-2-(1H-1,2,4-Triazolyl) acetophenone; A1JKQ; SCHEMBL76005; MLS000681496; 1-(2,4-Difluorobenzoylmethyl)-1H-1,2,4-triazole; 2',4'-Difluoro-2-(1,2,4-triazole)-1-yl acetophenone; CHEMBL2063495; SCHEMBL29445567; HMS2555A08; SMSSF-0017640; AKOS005208156; AC-5336; CS-W013099; HY-W012383; UK51060; DS-10468; SMR000269159; SY013731; NS00001891; EN300-265774; O10251; F093694; SR-01000492477; 2,4-Difluoro-?-(1H-1,2,4-triazolyl)acetophenone; SR-01000492477-1; Fluconazole EP Impurity E; Voriconazole EP Impurity A; Q27280148; 2,4-difluorophenyl-2-(1H-1,2,4-triazol-1-yl)ethanone; Fluconazole EP Impurity E;
Voriconazole EP Impurity A; 2',4'-Difluoro-alpha-(1H-1,2,4-triazol-1-yl)acetophenone; 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone, 95%; 2-(1H-1,2,4-Triazol-1-yl)-2\',4\'-difluoroacetophenone; 1-(2,4-difluoro phenyl)-2-(1H-1,2,4-triazole-1-yl)ethanone; 2 inverted exclamation mark ,4 inverted exclamation mark -Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone

Product application:2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone,86404-63-9,2-(1H-1,2,4-Triazol-1-yl)-2',4'-difluoroacetophenone,2,4-Difluoro-2-(1H-1,2,4-triazol-1-yl)acetophenone,Fluconazole intermediate,Voriconazole starting material,Isavuconazole precursor,Antifungal API intermediate,Triazole antifungal building block,Fluorinated heterocyclic building block,Broad spectrum antifungal intermediate,Anti-dandruff agent precursor,Industrial biocide raw material,Agricultural triazole fungicide intermediate,Crop protection chemical building block,Wood preservative intermediate,Fine chemical raw material,High purity 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone 99%,2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone manufacturer China,CAS 86404-63-9 supplier,Suzhou Health Chemicals fluorochemicals,Fluconazole intermediate wholesale bulk export

 

2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone serves as an indispensable, high-purity fluorinated heterocyclic building block, vital pharmaceutical active pharmaceutical ingredient (API) intermediate, and versatile agrochemical synthon extensively utilized across antifungal therapeutics, personal care formulations, crop protection chemistry, and industrial antimildew engineering sectors. In commercial pharmaceutical manufacturing and clinical medicinal chemistry, functioning as the foundational structural backbone possessing both a 2,4-difluorophenyl moiety and a 1,2,4-triazole heterocycle, it provides high targeted binding affinity toward fungal cytochrome P450 lanosterol 14alpha-demethylase (CYP51), selectively disrupting fungal ergosterol biosynthesis and compromising fungal membrane integrity; it represents the premier, irreplaceable starting raw material for industrial synthesis of blockbuster broad-spectrum antifungal agents, most notably Fluconazole, Voriconazole, and Isavuconazole, which are frontline clinical treatments for invasive candidiasis, cryptococcal meningitis, and refractory aspergillosis. In personal care and cosmeceutical applications, this molecule functions as a critical synthetic precursor for high-performance anti-dandruff actives and scalp conditioning agents designed to inhibit Malassezia colonization in hair care formulations. In sustainable agronomy and plant protection, it is an essential heterocyclic precursor for synthesizing modern triazole crop fungicides that deliver curative and preventive control against powdery mildew, sheath blight, and rust diseases across grain and fruit crops. In materials protection and preservation technologies, its derivatives are widely formulated into eco-friendly wood preservatives, anti-fungal bamboo coatings, premium furniture finishes, leather protective sealants, and anti-mildew architectural paints to prevent microbial deterioration. Furthermore, in functional adhesive sealants, specialty graphic printing inks, and biocidal water-treatment additives for petroleum extraction and industrial cooling circuits, polymers and organometallic complexes derived from 2,4-Difluoro-alpha-(1H-1,2,4-triazolyl)acetophenone deliver superior broad-spectrum antifungal durability, environmental stability, and multi-industry chemical resilience.