(3AS,4S,7R,7AS)-6-BENZYL-2,2-DIMETHYLTETRAHYDRO-4H-4,7-METHANO[1,3]DIOXOLO[4,5-D][1,2]OXAZINE

Product Details

CAS No:155855-51-9

MF:C15H19NO3

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:4,7-Methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine, tetrahydro-2,2-dimethyl-6-(phenylmethyl)-, (3aS,4S,7R,7aS)-;Ticagrelor Impurity 187;Ticagrelor Impurity 228;Tetrahydro-2,2-dimethyl-6-phenylmethyl-(3aS,4S,7R,7aS)-4,7-methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine;Tetrahydro-2,2-dimethyl-6-phenylmethyl-;(1R,2S,6S,7S)-9-Benzyl-4,4-dimethyl-3,5,8-trioxa-9-azatricyclo[5.2.1.0~2,6~]decane;TicagrelorImpurity1Chemicalbook87; 155855-51-9; (3AS,4S,7R,7AS)-6-BENZYL-2,2-DIMETHYLTETRAHYDRO-4H-4,7-METHANO[1,3]DIOXOLO[4,5-D][1,2]OXAZINE; Ticagrelor Impurity 228; SCHEMBL15058360; G89563; (3aS,4S,7R,7aS)-Tetrahydro-2,2-dimethyl-6-(phenylmethyl)-4,7-methano-4H-1,3-dioxolo[4,5-d][1,2]oxazine

Product application:(3aR,4S,7R,7aS)-6-benzyl-2,2-dimethyltetrahydro-4H-4,7-methano[1,3]dioxolo[4,5-d][1,2]oxazine,155855-51-9,(3AS,4S,7R,7AS)-6-BENZYL-2,2-DIMETHYLTETRAHYDRO-4H-4,7-METHANO[1,3]DIOXOLO[4,5-D][1,2]OXAZINE,Chiral oxazine derivative,Hetero-Diels-Alder adduct,Carbocyclic nucleoside precursor,Carbasugar building block,Chiral bicyclic oxazine,Pharmaceutical grade chiral building block,Antiviral API intermediate,Targeted oncology synthetic intermediate,Glycosidase inhibitor precursor,Asymmetric synthesis synthon,Chiral pharmaceutical intermediate,Enantiopure heterocyclic reagent,Fine organic chemical intermediate,High purity chiral oxazine 99%,CAS 155855-51-9 manufacturer China,155855-51-9 supplier,Suzhou Health Chemicals chiral building blocks,(3aR,4S,7R,7aS)-6-benzyl-2,2-dimethyltetrahydro-4H-4,7-methano[1,3]dioxolo[4,5-d][1,2]oxazine wholesale bulk export

 

(3AS,4S,7R,7AS)-6-BENZYL-2,2-DIMETHYLTETRAHYDRO-4H-4,7-METHANO[1,3]DIOXOLO[4,5-D][1,2]OXAZINE serves as an indispensable, ultra-pure enantiopure bicyclic building block, premier chiral synthon for asymmetric carbocyclic nucleoside synthesis, and versatile polycyclic intermediate extensively utilized across antiviral drug development, targeted clinical oncology therapeutics, chemical glycobiology, and advanced asymmetric catalytic synthesis sectors. In synthetic medicinal chemistry and active pharmaceutical ingredient (API) manufacturing, functioning as a strategically designed hetero-Diels-Alder cycloadduct derived from functionalized cyclopentadiene scaffolds, its molecular architecture incorporates four contiguous stereocenters (3aS, 4S, 7R, 7aS) embedded within a rigid methano-bridged framework, flanked by an acetonide-protected cis-diol and an N-benzyl-stabilized oxazine ring; through selective catalytic cleavage of the cleavable N-O linkage followed by controlled functional-group transformations, it provides direct, stereospecific access to densely functionalized chiral aminocyclopentanols, carbasugars, and carbocyclic nucleosides without requiring cumbersome optical resolution protocols, serving as a foundational intermediate for synthesizing blockbuster antiviral therapeutics against hepatitis B, human immunodeficiency virus (HIV), hepatitis C, and novel RNA viruses, as well as targeted antineoplastic candidates. In chemical glycobiology and enzyme-targeted drug design, it acts as a premier chiral template for constructing potent, transition-state mimetic glycosidase and glycosyltransferase inhibitors, facilitating fundamental research into cell-surface glycan remodeling and tumor invasion pathways. In macromolecular science and advanced chiral materials engineering, its rigid structural derivatives are incorporated into optically active helical polymers and chiral stationary phases for preparative enantiomer chromatography and enantioselective fluorescent chemical sensing. In specialty high-performance polymers, the rigid three-dimensional cage-like methano-bridge structure is deployed to enhance glass transition temperatures and structural modulus in thermally stable optical films. Furthermore, in the discovery of chiral agrochemical crop protection agents, specialized structural adhesives, and selective coordination extraction systems for petroleum and natural gas fine chemical refining, molecular architectures engineered from this compound deliver extraordinary stereochemical fidelity, reaction selectivity, and broad multi-industry performance.