2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol

Product Details

CAS No:274693-55-9

MF:C10H19NO4

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:2-(6-Amino-2,2-dimethyl-tetrahydro-cyclopenta[1,3]dioxol-4-yloxy)-ethanol;2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol;Ticagrelor InterMediate1;Ticagrelor Related Compound III;Ticagrelor Related Compound IV;Ticagrelor Related Compound V;2-[[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol;Ticagrelor Related Compound 87; 274693-55-9; 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol; 2-(((3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl)oxy)ethanol; RefChem:249061; 2-(((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol; MFCD16875500; GFJ3CDJ5F9; 1423768-25-5; 2-[[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol; AKOS015951194; 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-hexahydrocyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol; DS-13962; Ticagrelor Impurity 74; 2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-4H-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol; 2-{[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethanol; rel-2-(((3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethanol; WNYYMPICYAOQAE-RYPBNFRJSA-N; 2-[[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy]ethanol; TICAGREL; SCHEMBL1834548; DTXSID40433136; EX-7176; 2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyl-tetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol; 2-((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol; 2-[[(3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]-dioxol-4-yl]oxy]-1-ethanol; AC-28727; Ethanol, 2-[[(3aR,4S,6R,6aS)-6-aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]-; SY105000; DB-067793; CS-0055080; D82263; P11947; EN300-7414748; F216414; 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-; (3 aS,4R,6S,6aR)-6-(2-hydroxyethoxy)-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-amine; 2-((3 aR,4S,6R,6aS)-6-amino-2,2-dimethyl-tetrahydro-3 aH-cyclopenta[d][1,3]dioxol-4-yloxy)ethanol; 2-[[(3aS,4R,6S,6aR)-4-Aminotetrahydro-2,2-dimethyl-3aH-cyclopenta[d][1,3]dioxol-6-yl]oxy]ethanol; 2-{[(3aR,4S,6R,6aS)-6-Amino-2,2-dimethyltetrahydro-2H,3aH-cyclopenta[d][1,3]dioxol-4-yl]oxy}ethan-1-ol

Product application:2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol,274693-55-9,Ticagrelor intermediate,Ticagrelor amino alcohol intermediate,Ticagrelor free base intermediate,Ticagrelor cyclopentyl amine,2-(((3aR,4S,6R,6aS)-6-amino-2,2-dimethyltetrahydro-3aH-cyclopenta[d][1,3]dioxol-4-yl)oxy)ethan-1-ol,P2Y12 receptor antagonist precursor,Antiplatelet API intermediate,Antithrombotic API building block,Chiral amino alcohol intermediate,Pharmaceutical grade Ticagrelor intermediate,Cardiovascular therapeutic intermediate,Enantiopure cyclopentane synthon,Fine organic chemical intermediate,High purity Ticagrelor intermediate 99%,CAS 274693-55-9 manufacturer China,274693-55-9 supplier,Suzhou Health Chemicals chiral building blocks,Ticagrelor intermediate wholesale bulk export

 

2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol serves as an indispensable, ultra-pure enantiopure amino alcohol building block, premier active pharmaceutical ingredient (API) intermediate, and versatile chiral synthon extensively utilized across cardiovascular medicinal chemistry, commercial antithrombotic therapeutics manufacturing, and advanced asymmetric pharmaceutical synthesis sectors. In active pharmaceutical ingredient (API) manufacturing and pharmaceutical process chemistry, widely recognized as the free-base amino alcohol intermediate for the blockbuster antiplatelet drug Ticagrelor, its molecular framework incorporates four contiguous, impeccably defined stereocenters (3aR, 4S, 6R, 6aS) on a rigid cyclopentane ring containing an acetonide-protected cis-diol and an extended primary hydroxyethoxy handle; containing a highly reactive nucleophilic primary amine, it undergoes clean, regioselective nucleophilic aromatic substitution (SNAr) with functionalized dichloropyrimidine or triazolopyrimidine core synthons under mild conditions without epimerization; subsequent cyclization and mild acidic deprotection of the acetonide functionality yields the fully assembled Ticagrelor API without stereochemical erosion, supplying the global pharmaceutical supply chain for critical medications prescribed to manage acute coronary syndromes, prevent atherothrombotic events, and reduce stent thrombosis post-percutaneous coronary intervention (PCI). In receptor pharmacology and therapeutic drug discovery, this advanced synthon is employed to construct novel reversible purinergic P2Y12 receptor antagonists, allosteric binding probes, and nucleoside mimetic scaffolds. In biomaterials and functional macromolecular engineering, its chiral amino-diol ether backbone provides structural subunits for designing biocompatible polymeric matrices and targeted drug-release vehicles. Furthermore, in specialized chiral stationary phases and asymmetric coordination complexes for fine chemical synthesis, chemical architectures engineered from this compound deliver extraordinary stereochemical fidelity, coupling efficiency, and broad multi-industry performance.