4-Pentynoic acid

Product Details

CAS No:6089-09-4

MF:C5H6O2

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:UN 3261 8/PG II

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:4-Pentynoic acid, 95&percnt:;Propargylacetic acid, 2-Propargylethanoic acid;Pent-4-yn-1-oic acid;pent-4-yn-1-oicacid;PROPARGYLACETIC ACID;4-PENTYNOIC ACID;TIMTEC-BB SBB009121;4-Pentynoicacid,98%; 4-PENTYNOIC ACID; 6089-09-4; DTXSID20209730; RefChem:100316; DTXCID70132221; 228-028-0; Pent-4-ynoic acid; Propargylacetic acid; 4-pentynoicacid; Pent-4-yn-1-oic acid; MFCD00004407; EINECS 228-028-0; BRN 1742047; 4-02-00-01693 (Beilstein Handbook Reference); EN300-115626; pent4-ynoic acid; 4-Pentynoic a; Pent-4-yn-1-oicacid; BB 0260835; FT-0619364; 4-Pentynoic acid, 95%; SCHEMBL8803; SCHEMBL968764; orb1224476; orb1310475; SCHEMBL2025525; SCHEMBL10797809; MLBYLEUJXUBIJJ-UHFFFAOYSA-; 2WV768V33F; HY-Y1230; BBL103677; SBB009121; AKOS000188069; CS-W008784; FP01965; GS-6696; BP-14236; 4-Pentynoic acid, purum, >=97% (GC); DB-053734; DB-367931; NS00034491; P2341; ST51016255; T0580; F164204; Q27455468; Z295890062; InChI=1/C5H6O2/c1-2-3-4-5(6)7/h1H,3-4H2,(H,6,7)

Product application:4-Pentynoic acid,6089-09-4,Pent-4-ynoic acid,Propargylacetic acid,Terminal alkyne carboxylic acid,Click chemistry reagent,CuAAC reaction building block,Bioorthogonal chemistry reagent,Pharmaceutical grade 4-Pentynoic acid,ADC linker precursor,PROTAC chemical linker,Peptide alkyne modification tag,Bioconjugation crosslinker,Antifungal drug intermediate,Targeted oncology API intermediate,Functional polymer monomer,Thiol-yne photopolymerization monomer,Self-assembled monolayer SAM reagent,UV curable resin crosslinker,Fine chemical intermediate,High purity 4-Pentynoic acid 99.5%,4-Pentynoic acid manufacturer China,CAS 6089-09-4 supplier,Suzhou Health Chemicals specialty chemicals,4-Pentynoic acid wholesale bulk export

 

4-Pentynoic acid serves as an indispensable bifunctional terminal alkyne building block, premier click chemistry reagent, and versatile biological linker extensively utilized across biopharmaceuticals, antibody-drug conjugate (ADC) engineering, targeted PROTAC therapeutics, advanced polymer synthesis, and specialty functional materials sectors. In commercial pharmaceutical manufacturing and bioorthogonal chemistry, combining a reactive terminal acetylene group and a terminal carboxylic acid, it represents a foundational benchmark synthon for executing copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry to form robust 1,2,3-triazole linkages under physiological conditions; it is globally employed to functionalize therapeutic peptides, monoclonal antibodies, fluorescent molecular imaging probes, and nucleosides, functioning as an essential flexible spacer for synthesizing ADC payload-linker constructs, heterobifunctional PROTAC degraders, and novel antifungal or antineoplastic active pharmaceutical ingredients. In polymer chemistry and radiation curing, this monomer is polymerized via efficient thiol-yne step-growth photopolymerization to engineer specialized crosslinked networks characterized by elevated glass transition temperatures, high refractive index, and low polymerization shrinkage, serving as a critical component in 3D printing photopolymers, dental composites, and optical resins. In semiconductor nanotechnology, it is utilized to construct self-assembled monolayers (SAMs) on noble metal and silicon surfaces, providing precise molecular-level surface functionalization for biosensing devices and microelectronic interfaces. In functional adhesives, high-performance automotive coatings, and specialty elastomeric sealants, it acts as a graftable crosslinking modifier that optimizes cohesive strength and interfacial substrate bonding. In sustainable agrochemical discovery, its terminal alkyne motif enables the synthesis of highly potent heterocyclic crop protection agents and biostimulants. Furthermore, in functional textile grafting treatments, wear-resistant leather topcoats, eco-friendly wood composite adhesives, and industrial corrosion inhibition formulations for oil and gas infrastructure, chemical architectures derived from 4-Pentynoic acid deliver exceptional chemoselectivity, structural stability, and broad multi-industry performance.