2-Hydroxy-6-chloroquinoxaline

Product Details

CAS No:2427-71-6

MF:C8H5ClN2O

Appearance:off-white or light-pink crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:2-HYDROXY-6-CHLOROQUINOXALINE;6-CHLORO-2(1H)-QUINOXALINONE;6-CHLORO-2-HYDROXYQUINOXALINE;6-chloro-2(1h)-quinoxalinon;6-chloroquinoxalin-2(1H)-one;2(1H)-Quinoxalinone,6-chloro-;6-Chloroquinoxalin-2-ol;6-Chloroquinoxaline-2(1H)-one; 2-Hydroxy-6-chloroquinoxaline; 2(1H)-Quinoxalinone, 6-chloro-; RefChem:473309; 813-002-9; 2427-71-6; 6-CHLORO-2(1H)-QUINOXALINONE; 6-chloroquinoxalin-2-ol; 6-chloro-1H-quinoxalin-2-one; 6-Chloro-2-hydroxyquinoxaline; 6-Chloroquinoxalin-2(1H)-one; 39267-06-6; MFCD06200849; MFCD03265373; 6-chloro-1,2-dihydroquinoxalin-2-one; 6-chloro-2-quinoxalinol; SCHEMBL7757513; SCHEMBL8530324; SCHEMBL9257557; DTXSID7062409; SCHEMBL30665754; Hydroxy quinoxaline (CGA 290291); AKOS006229832; AKOS015850358; DS-0252; FS-3222; GS-3398; AC-11450; SY031963; NS00067667; EN300-306612; S10160; F079341; doi:10.14272/SJAZZQLTKBYDHN-UHFFFAOYSA-N.1; Z1198166471

Product application:2-Hydroxy-6-chloroquinoxaline,2427-71-6,6-Chloroquinoxalin-2-ol,6-Chloro-2-hydroxyquinoxaline,6-Chloro-2(1H)-quinoxalinone,6-Chloro-1,2-dihydroquinoxalin-2-one,Quizalofop-P-ethyl intermediate,Quizalofop intermediate,Quizalofop-P-tefuryl precursor,Aryloxyphenoxypropionate herbicide building block,Crop protection chemical intermediate,Quinoxaline heterocyclic building block,Pharmaceutical grade 6-Chloroquinoxalin-2-ol,Targeted oncology API intermediate,Kinase inhibitor building block,Antibacterial chemical precursor,Fine organic chemical intermediate,Fluorescent dye building block,High purity 2-Hydroxy-6-chloroquinoxaline 99%,2-Hydroxy-6-chloroquinoxaline manufacturer China,CAS 2427-71-6 supplier,Suzhou Health Chemicals specialty chemicals,Quizalofop intermediate wholesale bulk export

 

2-Hydroxy-6-chloroquinoxaline serves as an indispensable, high-purity halogenated quinoxaline building block, premier agrochemical active ingredient precursor, and versatile heterocyclic synthon extensively utilized across modern crop protection chemistry, commercial herbicide manufacturing, clinical medicinal discovery, functional colorants, and advanced chemical materials sectors. In sustainable agricultural science and commercial crop protection manufacturing, universally known as 6-Chloroquinoxalin-2-ol, it represents the foundational, irreplaceable core intermediate for the multi-ton commercial synthesis of blockbuster aryloxyphenoxypropionate post-emergence selective herbicides, including Quizalofop-P-ethyl, Quizalofop-ethyl, and Quizalofop-P-tefuryl; utilizing the tautomeric reactivity of its hydroxyl and lactam moieties under mild alkaline conditions, it undergoes regioselective etherification coupling with chiral 4-hydroxyphenoxypropionic acid esters to construct the essential pharmacophore that selectively inhibits plant acetyl-CoA carboxylase (ACCase), blocking de novo fatty acid biosynthesis to achieve systemic eradication of annual and perennial gramineous weeds in broadleaf soybean, cotton, canola, and peanut fields without inducing phytotoxicity to host crops. In synthetic medicinal chemistry and pharmaceutical API development, its rigid electron-deficient quinoxaline framework serves as a vital pharmacophore for assembling targeted receptor tyrosine kinase inhibitors, antineoplastic therapeutics, novel antimycobacterial agents, and broad-spectrum antiviral candidates. In functional colorants and optoelectronic materials, it functions as a conjugated intermediate for synthesizing light-fast heterocyclic azo dyes, liquid crystal alignment dopants, and fluorophores. In polymer science, its derivatives are explored as heat-resistant comonomers for specialized polyquinoxalines and high-temperature thermal stabilizers for engineering polymers. Furthermore, in heavy-duty protective coatings, structural adhesives, anti-aging rubber additives, and specialized acid-corrosion inhibitors for petroleum and natural gas exploration pipelines, molecular architectures engineered from 2-Hydroxy-6-chloroquinoxaline deliver exceptional heterocyclic stability, chemical resistance, and broad multi-industry performance.