Sauchinone

Product Details

CAS No:177931-17-8

MF:C20H20O6

Appearance:white or light-yellow crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:KGS

Synonyms:(5aR,7R,8S,8aR,14aS,14bR)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;(5aα,7α,8β,8aβ,14aS*,14bβ)-5a,6,7,8,8a,14b-Hexahydro-7,8-dimethyl-5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4′,5′-g]xanthen-5-one;Sauchinone, 98%, from Saururus chinensis (Lour. ) Baill;SAUCHINONE;(5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro- 5H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one;5H-Benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one, 5a,6,7,8,8a,14b-hexahydro-7,8-dimethyl-, (5aR,7R,8S,8aR,14aS,14bR)-;Sauchinone >=98% (HPLC);AI3 00896; sauchinone; 177931-17-8; (1S,12R,13S,14R,16R,23R)-13,14-dimethyl-2,6,8,20,22-pentaoxahexacyclo[10.10.1.01,19.03,11.05,9.016,23]tricosa-3,5(9),10,18-tetraen-17-one; DTXSID701318550; (1S,12R,13S,14R,16R,23R)-13,14-dimethyl-2,6,8,20,22-pentaoxahexacyclo(10.10.1.01,19.03,11.05,9.016,23)tricosa-3,5(9),10,18-tetraen-17-one; RefChem:181519; DTXCID301748357; MFCD08702698; (5aR,5a1R,7R,8S,8aR,14aS)-7,8-Dimethyl-5a,5a1,6,7,8,8a-hexahydro-5H-benzo[kl]bis([1,3]dioxolo)[4,5-b:4',5'-g]xanthen-5-one; Sauchinone (Standard); CHEMBL520054; orb1300204; orb3140557; SCHEMBL1498622; HY-N0613R; HY-N0613; MSK158028; AKOS030631736; CCG-268111; EBC-615898; FS73944; T6S1572; AC-34741; AS-77171; CS-0009611; (1S,12R,13S,14R,16R,23R)-13,14-dimethyl-2,6,8,20,22-pentaoxahexacyclo[10.10.1.0^{1,19}.0^{3,11}.0^{5,9}.0^{16,23}]tricosa-3(11),4,9,18-tetraen-17-one; (5aR,7R,8S,8aR,14aS,14bR)-7,8-Dimethyl-5a,6,7,8,8a,14b-hexahydro-2H,5H,11H-benzo[kl]bis[1,3]dioxolo[4,5-b:4',5'-g]xanthen-5-one

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Sauchinone is a prominent bioactive tetrahydrofuran-type lignan isolated from the roots and rhizomes of Saururus chinensis, exhibiting distinct pharmacological and physiological utility across biomedical discovery, nutritional therapeutics, and advanced skincare formulation. In biomedical research and preclinical drug development, sauchinone is widely investigated as a potent natural activator of the AMP-activated protein kinase (AMPK) signaling cascade via upstream LKB1 regulation, demonstrating remarkable therapeutic potential in downregulating inducible nitric oxide synthase, cyclooxygenase-2, and inflammatory cytokines. This mechanism underpins its protective role against acute liver injury, non-alcoholic steatohepatitis, hepatic fibrogenesis, and lipid metabolism dysfunction, while its capacity to suppress intracellular reactive oxygen species accumulation and cellular ferroptosis provides substantial cytoprotection in neuronal and cardiovascular ischemia-reperfusion models. In cosmetic dermatology and personal care industries, sauchinone functions as a high-performance botanical active in premium anti-aging, firming, and skin-barrier restoring formulations, acting to suppress UVB-induced matrix metalloproteinase production, protect dermal collagen networks, mitigate oxidative photo-damage, and alleviate inflammatory hyperpigmentation. In nutritional science and dietary supplement research, it serves as a valuable functional component for developing metabolic health interventions and liver detox support formulations. In specialty organic synthesis and chemical biology, the rigid stereochemically defined polycyclic oxygenated core of sauchinone provides an ideal template and natural molecular scaffold for exploring structure-activity relationships, synthesizing targeted autophagy modulators, and engineering bioconjugate research probes.