Hexadecanedioic acid 1-methyl ester

Product Details

CAS No:18451-85-9

MF:C17H32O4

Appearance:White or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:Hexadecanedioic acid 1-methyl ester;Hexadecanedioic acid hydrogen 1-methyl ester;15-(methoxycarbonyl)pentadecanoicaci;monomethyl hexadecanedioate;Hexadecanedioic acid 1-methyl este;Hexadecanedioicacid monomethyl ester;16-Methoxy-16-oxohexadecanoic acid,16-Methoxy-16-oxohexadecanoic acid,16-methoxy-16-oxohexadecanoic acid; 18451-85-9; Hexadecanedioic acid 1-methyl ester; MFCD00673467; hexadecanedioic acid monomethyl ester; SCHEMBL905415; PPYYVFBDKRFTDQ-UHFFFAOYSA-N; 16-Methoxy-16-oxohexadecanoicacid; BS-46510; SY417931; DB-097848; F71570,300.400,C17H32O4,

Product application:Hexadecanedioic acid 1-methyl ester,18451-85-9,Suzhou Health Chemicals,Monomethyl hexadecanedioate,Hexadecanedioic acid monomethyl ester,16-Methoxy-16-oxohexadecanoic acid,Insulin degludec intermediate,Semaglutide side chain,Long-chain dicarboxylic acid derivative,Pharmaceutical intermediates supplier,Buy Hexadecanedioic acid 1-methyl ester,CAS 18451-85-9 factory,GLP-1 intermediate,High purity chemistry reagents

 

Hexadecanedioic acid 1-methyl ester (CAS 18451-85-9) is a highly critical long-chain aliphatic dicarboxylic acid monoester derivative primarily utilized as a premium pharmaceutical intermediate. It serves as the core precursor for synthesizing the fatty acid side chains of long-acting insulin analogues and GLP-1 receptor agonists, such as Insulin Degludec and Semaglutide. By modifying the terminal amino groups of proteins or peptides, this compound significantly enhances their binding affinity to serum albumin, thereby extending the drug's in vivo half-life and achieving sustained therapeutic efficacy. Beyond biopharmaceuticals, it also finds strategic applications in advanced organic synthesis, biomaterial modification, and specialty surfactant formulations.