L-Ornithine alpha-Ketoglutarate(2:1); OKG

Product Details

CAS No:5144-42-3

MF:2(C5H12N2O2).C5H6O5

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:L-Ornithine α-Ketoglutarate Monohydrate;L-ORNITHINE-KETOGLUTARATE DIHYDRATE;L-ORNITHINE A-KETOGLUTARATE (2:1);L-ORNITHINE-A-KETOGLUTARATE(2:1) DIHYDRATE;L-ORNITHINE ALPHA-KETOGLUTARATE (2:1) DIHYDRATE;Ornithine α-ketoglutaric acid;Ornithine/α-ketoglutaric acid,(2:1);(2S)-2,5-bis(azanyl)pentanoic acid

Product application:L-Ornithine 2-oxoglutarate (2:1), Bis(L-ornithine) 2-oxoglutarate, OKG 2:1, CAS 5144-42-3, Clinical OKG salt, High bioavailability Ornithine ketoglutarate, Protein anabolism stimulator, Anti-proteolytic agent, Anabolic hormone secretagogue, Growth hormone release trigger, Glutamine pool repletion, Severe burn therapy excipient, Surgical trauma nutritional formulation, Decubitus ulcer healing agent, Hepatic encephalopathy treatment raw material, Ammonia clearance agent, FSMP medical nutrition ingredient, Elite sports bodybuilding supplement, Muscle recovery and repair powder, Sarcopenia reversal nutrient, Pharma grade L-Ornithine 2-oxoglutarate 2:1, High purity OKG 2:1 bulk supplier, Wholesale CAS 5144-42-3 manufacturer

 

L-Ornithine 2-oxoglutarate is a high-bioavailability bioactive salt synthesized from two moles of L-ornithine and one mole of alpha-ketoglutarate, representing the gold standard OKG form validated in clinical nutrition and metabolic therapeutics. In burn surgery, acute intensive care, and surgical convalescence, it demonstrates robust anti-catabolic and anabolic properties by triggering the endogenous secretion of growth hormone and insulin, while serving as a vital biochemical reservoir for rapidly replenishing depleted intramuscular glutamine pools, thereby reversing negative nitrogen balance and preventing muscle cachexia during severe metabolic trauma. In wound healing pathology, it accelerates proline synthesis, collagen matrix deposition, and microvascular regeneration, significantly shortening recovery timelines for severe thermal burns, diabetic foot ulcers, and chronic pressure wounds. In hepatology and metabolic nitrogen control, the dual ornithine moieties actively stimulate the hepatic urea cycle to convert toxic free blood ammonia into excretable urea, while the keto-glutarate moiety enters the citric acid cycle for cellular ATP synthesis, playing an indispensable role in mitigating hyperammonemia. Furthermore, in elite athletic nutrition and specialized medical foods, it is extensively incorporated to accelerate post-workout myofibrillar repair, increase lean muscle volume, mitigate physical exhaustion, and preserve physical vitality in geriatric populations.