Tocofersolan; Tocopherosolan; TPGS; Vitamin E-TPGS

Product Details

CAS No:9002-96-4

MF:C33H54O5.(C2H4O)n

Appearance:off-white or yellowish waxy solid

Specification:USP

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:DL-A-TOCOPHEROL POLYETHYLENE GLYCOL SUCCINATE;DL-ALPHA-TOCOPHEROL POLYETHYLENE GLYCOL SUCCINATE;d-alpha-tocopheryl polyethylene glycol succinate;alpha-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2h-1-benzopyran-6-yl)oxy)-1,4-dioxobutanol poly(ethylene glycol) succinate;tocofersolan;tocopherosolan;2-ethanediyl),.alpha.-[4-[[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzoPoly(oxy-1;poly(oxy-1,2-ethanediyl),alpha-(4-((3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12; [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl] 2-hydroxyethyl butanedioate; butanedioic acid [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanyl] ester 2-hydroxyethyl ester; succinic acid [2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)chroman-6-yl] ester 2-hydroxyethyl ester; 32408-94-9; 58829-13-3; 9002-96-4; 30999-06-5; D 1T; (+)-alpha-Tocopheryl polyethylene glycol 1000 succinate

Nutrient supplement & Nutritional additive, Food additive, Cosmetics additive, Personal-care additive, Pharmaceutical excipient.

Tocofersolan is a water-soluble derivative of vitamin E, which is formed by the reaction of the carboxyl group of vitamin E succinate and the hydroxyl group of polyethylene glycol. Because it contains both the lipophilic group of vitamin E and the long hydrophilic chain of polyethylene glycol, it has good surfactant properties and water solubility, and can significantly increase the absorption of poorly soluble drugs in the gastrointestinal tract and improve bioavailability. Tocofersolan can be used as a solubilizer, absorption promoter, emulsifier, plasticizer, and carrier of fat-soluble drug delivery system, which can increase the bioavailability of drugs by 6 to 9 times, thereby reducing the damage of drugs to the liver and improving the efficacy. Due to its unique water-soluble properties, Tocofersolan is currently widely used in pharmaceutical excipients, health care food ingredients, cosmetic excipients and other industries.