4-Dimethylaminopyridine

Product Details

CAS No:1122-58-3

MF:C7H10N2

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:UN 2811 6.1/PG II

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:AKOS BBS-00004314;AURORA KA-6495;26DCLPY;4-(Dimethylamino)pyridine, ReagentPlus, 99%;N,N'-DIMEHTYL-4-PYRIDINAMINE;4-(Dimethylamino)PyridineForSynthesis;4-Dimethylaminopyridine,>99%;Dmap(4-Dimethylaminopyridine); 4-Dimethylaminopyridine; 1122-58-3; N,N-Dimethylpyridin-4-amine; dmap; 4-(Dimethylamino)pyridine; 4-Pyridinamine, N,N-dimethyl-; DTXSID0044369; PFP1R6P0S8; 4-DMAP; DTXCID8024369; 4-[dimethylamino]pyridine; RefChem:98776; 214-353-5; p-Dimethylaminopyridine; N,N-DIMETHYL-4-PYRIDINAMINE; N-(4-Pyridyl)dimethylamine; N,N-Dimethyl-4-aminopyridine; Pyridine, 4-(dimethylamino)-; MFCD00006418; 887925-31-7; 4-DIMETHYLAMINO PYRIDINE; 4-dimethylamino-pyridine; 4-(dimethylamino)-pyridine; Valaciclovir EP Impurity G; 4-Dimethylaminopyridine (DMAP); 4-Dimethylaminepyridine; dimethyl-4-pyridylamine; 4-(dimethylamino) pyridine; dimethyl-pyridin-4-yl-amine; CHEMBL3561645; PYRIDINE, 4-DIMETHYLAMINO-; N,N-dimethyl-N-(4-pyridinyl)amine; 4-Pyridinamine,N,N-dimethyl-, hydrobromide, hydrate (1:1:2); CCRIS 6176; gamma-(Dimethylamino)pyridine; 4-dimethylaminopyridin; dimethylpyridin-4-ylamine; EINECS 214-353-5; UNII-PFP1R6P0S8; BRN 0110354; n,n'-dimethyl-4-pyridinamine; 4-(n,n-dimethylamino)pyridine; JGD; 4dimethylaminopyridine; 4-dimethlaminopyridine; 4-dimethyaminopyridine; 4-dimethylaminopridine; 4-dimethylaminopyridme; 4-dimethylammopyridine; 4-dimetylaminopyridine; 4-dimethlyaminopyridine; 4-dimethylaminopiridine; 4-dimethylaminopryidine; 4-dimethylamino pyridin; 4-dimetylamino-pyridine; 4-dimethylarninopyridine; p-dimethylamino pyridine; p-dimethylamino-pyridine; 4 -dimethylaminopyridine; 4(dimethylamino)pyridine; 4- dimethylaminopyridine; 4-di methylaminopyridine; 4-di-methylaminopyridine; 4-dimethy-laminopyridine; 4-dimethylamine pyridine; 4-dimethylaminopyridine-; para-dimethylaminopyridine; 4-(dimethyamino)pyridine; 4-dimetylamino- pyridine; 4(dimethylamino) pyridine; 4-(dimethyiamino)pyridine; 4-(dimethyl)aminopyridine; 4-(dimethylamino)pryidine; 4-di-methylamino-pyridine; 4-dimethylamino- pyridine; SCHEMBL189; 4-(dimethylarnino)pyridine; dimethyl-pyridin-4yl-amine; dimethylpyridin-4-yl-amine; p-(dimethylamino)-pyridine; DMAP [MI]; 4- (dimethylamino)pyridine; 4-(dimethlyamino)-pyridine; 4-(dimethyl amino)pyridine; 4-(dimethyl-amino)pyridine; n,n-dimethylpyridin-4-amin; p-N,N-dimethylaminopyridine; 4-(Dimethylamino-)pyridine; Valaciclovir impurity G CRS; 4-(dimethyl amino) pyridine; 4-(dimethyl-amino)-pyridine; N,N dimethyl-4-pyridinamine; N,N-dimethyl 4-pyridinamine; 4-(Dimethylamino)- pyridine; N,N-Dimethy-4-aminopyridine; 4(N,N dimethylamino)pyridine; 4(N,N-dimethylamino)pyridine; 5-22-09-00112 (Beilstein Handbook Reference); N,N-dimethyl-4-pyridineamine; N,N-dimethylpyridine-4-amine; SCHEMBL746483; 4-(N,N-dimethyamino)pyridine; 4-(N,N-dimetylamino)pyridine; n,n-dimethyl-4-amino pyridine; N,N-dimethyl-pyridin-4-amine; N,N-dimethylpyridin -4-amine; 4-(N,N-dimethyiamino)pyridine; 4-(N,N-dimethyl)aminopyridine; N, N-dimethyl-4-aminopyridine; orb2664816; orb3026002; SCHEMBL1628057; SCHEMBL3821459; .gamma.-(Dimethylamino)pyridine; para-N,N-dimethylamino-pyridine; 4-(n,n,-dimethylamino)pyridine; 4-(n,n-dimethylamino)-pyridine; 4-Dimethykaminopyridine (DMAP); 4-Dimethylaminopyridine, Prilled; 4-(N, N-dimethylamino)pyridine; 4-(N,N dimethylamino)-pyridine; 4-(N,N'-dimethylamino)pyridine; 4-(N,N-dimethyl amino)pyridine; 4-(N,N-dimethyl-amino)pyridine; 4-(N,N-dimethylamino) pyridine; N,N-dimethyl-pyridin-4-yl-amine; 4-(N, N-dimethylamino) pyridine; 4-(N, N-dimethylamino)-pyridine; 4-(N,N'-dimethylamino) pyridine; CHEBI:182593; para-(N,N-dimethylamino) pyridine; (4-DMAP);4-Dimethylaminopyridine; 4-(dimethylamino)pyridine (DMAP); 4-(Dimethylamino)pyridine; >99%; 4--(N,N'-dimethylamino) pyridine; HY-Y1089; STR00352; Tox21_302184; BDBM50556493; CX1367; EBC-14686; MSK001144; SBB008765; STK865133; AKOS000120170; CS-W008903; DMAP; N4,N4-Dimethylpyridin-4-amine; FD00992; MSK001144-100A; PS-4600; SB40777; MSK001144-1000A; NCGC00257546-01; 4-(N; AC-13385; BP-21319; DA-19672; PD074147; 4-(Dimethylamino)pyridine, prilled, 99%; CAS-1122-58-3; DB-016064; D1450; NS00008104; ST51047398; EN300-20577; T65640; AR-360/40355729; F001704; Q229897; 4-(Dimethylamino)pyridine, purum, >=98.0% (NT); 4-(Dimethylamino)pyridine, ReagentPlus(R), >=99%; 4-(Dimethylamino)pyridine, puriss., >=99.0% (NT); F0001-0270; Z104478964; 4-(Dimethylamino)pyridine, pharmaceutical impurity standard; VALACICLOVIR HYDROCHLORIDE IMPURITY G [EP IMPURITY]; 4-(Dimethylamino)pyridine Solution in Acetonitrile, 1000ug/mL; 4-(Dimethylamino)pyridine Solution in Acetonitrile, 100ug/mL; VALACICLOVIR HYDROCHLORIDE HYDRATE IMPURITY G [EP IMPURITY]; InChI=1/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H; Valaciclovir impurity G, European Pharmacopoeia (EP) Reference Standard; 4-(Dimethylamino)pyridine, ChemDose(TM) tablets, Loading: 0.04 mmol tablet.

Product application:4-Dimethylaminopyridine,1122-58-3,DMAP,4-N,N-Dimethylaminopyridine,N,N-Dimethyl-4-pyridinamine,p-Dimethylaminopyridine,Super nucleophilic catalyst,Acylation catalyst,Steglich esterification catalyst,Amidation promoter,Peptide coupling co-catalyst,Steroid synthesis reagent,Paclitaxel synthesis catalyst,Polyurethane catalyst,Polycarbonate synthesis agent,Organic base catalyst,High purity DMAP 99.5%,Low pyridine DMAP,CAS 1122-58-3 supplier,4-Dimethylaminopyridine manufacturer China,Suzhou Health Chemicals specialty catalysts,DMAP wholesale bulk export

 

4-Dimethylaminopyridine is widely utilized across commercial active pharmaceutical ingredient synthesis, complex natural product total synthesis, peptide and macromolecular fragment coupling, sterically hindered organic esterification and amidation, functional polyurethane and polycarbonate polymerization catalysis, and fine agrochemical manufacturing sectors. In process organic chemistry and pharmaceutical engineering, universally recognized in synthetic methodologies as DMAP, it serves as the benchmark hyper-nucleophilic acylation catalyst; the strong electron-donating resonance of its 4-dimethylamino substituent dramatically elevates the nucleophilicity of the pyridine ring nitrogen, driving kinetic acceleration factors thousands of times higher than unmodified pyridine; under ambient, neutral-to-mild reaction conditions, it intercepts acyl chlorides, anhydrides, or activated carboxylic acids to form a transient, highly electrophilic 1-acyl-4-(dimethylamino)pyridinium intermediate; this reactive species readily undergoes clean acyl transfer onto stubborn, sterically congested nucleophiles, such as tertiary carbinols, hindered phenols, and bulky amines that are otherwise refractory to standard bases; this mechanism establishes it as the quintessential co-catalyst in Steglich esterifications, enabling reliable synthesis across oncology therapeutics including paclitaxel taxane core elaborations, cephalosporin antibiotic derivatizations, and corticosteroid synthetic sequences; in polymer materials engineering, it functions as an efficient curing catalyst for polyaddition reactions of isocyanates and polyols to modulate crosslinking network densities; furthermore, in bio-analytical chemistry, 4-Dimethylaminopyridine provides dependable catalytic turnover and derivatization efficiency across demanding industrial and chemical manufacturing operations.