(R)-(+)-2-Methyl-2-propanesulfinamide

Product Details

CAS No:196929-78-9

MF:C3H11CNOS

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:R- tert butyl sulfenaMide;(R)-(+)-T-BUTANESULFINAMIDE;(R)-(+)-T-BUTYLMETHYLSULFINAMIDE;(R)-(+)-T-BUTYLSULFINAMIDE;(R)-(+)-TERT-BUTYL SULPHINAMIDE;(R)-(+)-2-METHYL-PROPANE-2-SULFINIC ACID AMIDE;(R)-(+)-2-METHYL-2-PROPANESULFINAMIDE;(R)- (+)- 2-Methyl-2-propanesulphinaMide,"tert-Butylsulfinamide, (R)-(+)-","196929-78-9; (R)-(+)-2-Methyl-2-propanesulfinamide; (r)-2-methylpropane-2-sulfinamide; (R)-(+)-tert-Butylsulfinamide; (R)-tert-Butanesulfinamide; (r)-tert-butylsulfinamide; (r)-2-methyl-2-propanesulfinamide; (r)-(+)-tert-butanesulfinamide; DTXSID40449939; DTXCID10400759; ELLMAN'S SULFINAMIDES (R)-FORM; 676-338-3; 2-PROPANESULFINAMIDE, 2-METHYL-, (R)-; 2-Propanesulfinamide, 2-methyl-, (S(R))-; 7FEC1T720F; tert-Butylsulfinamide, (R)-(+)-; (R)-(+)-t-Butylsulfinamide; MFCD05861479; (R)-(+)-tert-Butyl sulfinamide; C4H11NOS; R)-(+)-tert-Butyl sulfinamide; (r)-(+)-tert-butyl sulphinamide; (R)-t-butylsulfinamide; (r)-t-butanesulfinamide; (R)-t-butyl sulfinamide; (R)-tert-butyl sulfinamide; (R)-tert.-butylsulfinamide; (R)-tert-butane sulfinamide; orb2940163; (R)-(-)-tert-butanesulfinamide; (R)-2-methyl propane-2-sulfinamide; (R)-2-methyl-2-propane-sulfinamide; (R)-2-Methyl-2-propanesulfin-amide; SBB056498; AKOS005259723; CS-W018485; FM10686; PB47675; (R)-(+)-2-methyl 2 propanesulfinamide; (R)-(+)-2-methylpropane-2-sulfinamide; (R)-(-)-2-methyl-2-propanesulfinamide; AS-12466; HY-40228; SY006657; (R)-(+)-2-methyl-2-propane sulfinamide; (R)-(-)-2-Methyl-2-propane-sulfinamide; (R)-2-methylpropane-2-sulfinic acid amide; (R)-2-methyl-propane-2-sulfinic acid amide; B2907; EN300-217228; (R)-(+)-2-Methyl-2-propanesulfinamide, 98%; (R)-(+)-tert-Butylsulfinamide;Ellman's Sulfinamide; Q27268198; (R)-(+)-2-Methyl-2-propanesulfinamide; (R)-N-tert-Butanesulfinamide;",121.200,C4H11NOS,

Product application:(R)-(+)-tert-Butylsulfinamide, (R)-2-methylpropane-2-sulfinamide, (R)-tert-Butylsulfinamide, (R)-Ellman's sulfinamide, CAS 196929-78-9, (R)-t-BuSA, chiral auxiliary, chiral sulfinamide, chiral amine synthesis, asymmetric synthesis reagent, pharmaceutical intermediates, high purity (R)-tert-Butylsulfinamide, pharma grade (R)-tert-Butylsulfinamide, chiral induction agent, (R)-tert-butylsulfinamide manufacturer, CAS 196929-78-9 supplier, chiral building block, asymmetric reduction agent, Suzhou Health Chemicals, Health Chem

 

(R)-(+)-tert-Butylsulfinamide serves as a highly versatile chiral auxiliary and crucial pharmaceutical intermediate extensively used in asymmetric synthesis within organic chemistry and drug discovery. Its primary function involves reacting with aldehydes or ketones to yield chiral N-tert-butanesulfinyl imines, which subsequently undergo diastereoselective additions with various nucleophiles (such as Grignard reagents, organolithium, and organozinc compounds) or reductions via catalytic hydrogenation. This process enables the high-stereoselectivity synthesis of enantiomerically pure primary and secondary chiral amines, α-/β-amino acids, amino alcohols, and nitrogen-containing heterocycles. In the pharmaceutical industry, it is widely utilized as a key chiral building block for synthesizing active pharmaceutical ingredients (APIs), including anti-cancer agents (such as KRAS and EGFR inhibitors), antivirals, central nervous system (CNS) drugs, and novel antibiotics. The sulfinyl group can be smoothly cleaved under mild acidic conditions without racemization, substantially improving step-efficiency and process scalability in industrial chiral drug manufacturing.