Calcium Orotate

Product Details

CAS No:22454-86-0

MF:C10H6CaN4O8

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, calcium salt (2:1);Bis(1,2,3,6-tetrahydro-2,6-dioxo-4-pyrimidinecarboxylic acid)calcium salt;CalciuM Orotate Dihydrate INN;CALCIUM OROTATE;OROTIC ACID CALCIUM SALT;calcium 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate;calcium oratate;Calciumorotatehadrate; Calcium orotate; 22454-86-0; Calora; Orotic acid calcium salt; calcium diorotate; UNII-990GJM86HY; Calciumorotat (TN); 990GJM86HY; OROTATE CALCIUM; 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, calcium salt (2:1); EINECS 245-009-2; CALCIUM OROTATE DEHYDRATE; DTXSID7066801; CALCIUM OROTATE [WHO-DD]; Calciumorotat; RefChem:122878; DTXCID6036706; 245-009-2; Calcium 2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate; 4-Pyrimidinecarboxylic acid, 1,2,3,6-tetrahydro-2,6-dioxo-, calcium salt(2:1); calcium;2,4-dioxo-1H-pyrimidine-6-carboxylate; MFCD00039119; C10H6CaN4O8; calcium bis(2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxylate); Calcium 1,2,3,6-tetrahydro-2,6-dioxopyrimidine-4-carboxylate; SCHEMBL422601; AKOS015901955; FC33878; AS-19004; SY317429; DB-264616; NS00083992; 2,4-Dioxo-1H-pyrimidine-6-carboxylate calcium; D08304; D70206; Calcium bis(2,6-dihydroxypyrimidine-4-carboxylate); Q27272160

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Calcium orotate serves as an indispensable, ultra-pure bioavailable organic chelated mineral compound, premier intracellular calcium delivery vehicle, and versatile cellular active ingredient extensively utilized across functional dietary supplements, clinical bone pharmaceuticals, advanced restorative cosmeceuticals, precision livestock nutrition, and biotechnology sectors. In functional food science and advanced dietary supplementation, universally recognized as a superior bioactive mineral transporter where calcium is stably coordinated to two natural orotic acid (vitamin B13) ligands, it circumvents the digestive degradation and poor membrane permeability characteristic of traditional inorganic calcium carbonate or citrate; this molecular complex traverses intestinal mucosal barriers and intact cell membranes without premature dissociation, directly delivering elementary calcium into osteocytes, chondrocytes, and myocardial cells without precipitating kidney stones or inducing gastrointestinal distress, making it the premier functional active for formulating high-potency bone-density tablets, joint mobility capsules, athletic mineral beverages, and clinical longevity supplements to reverse osteopenia, enhance bone mineral accretion, and maintain cardiac electrical conduction. In clinical pharmaceuticals and bone metabolism therapeutics, it functions as a targeted therapeutic raw material and medical food component for treating severe osteoporosis, osteoarthritis cartilage loss, delayed fracture union, and chronic cardiac muscle insufficiency. In personal care formulation and therapeutic skincare, it operates as a biomimetic calcium gradient regulator that stimulates epidermal keratinocyte differentiation, upregulates endogenous ceramide synthesis, accelerates cutaneous barrier repair, and diminishes inflammatory cytokines in post-procedure soothing creams and barrier-reinforcing anti-aging emulsions. In modern animal husbandry and aquaculture, adding this bio-chelated nutrient into feed formulations significantly optimizes calcium absorption in laying hens and crustaceans, preventing soft-shell eggs, improving skeletal strength, and accelerating cuticle hardening during molt cycles. Furthermore, in mammalian cell bioprocessing media supplementation, diagnostic biochemical assay reagents, and functional coordination chemistry, Calcium orotate delivers outstanding metabolic safety, superior membrane permeability, and broad multi-industry performance.