trans,trans-Farnesyl Bromide

Specifications:

Item

Standards

Appearance:

Light-yellow to brown transparent liquid

Odor:

Characteristic

Identification:

IR/HPLC/Mass/NMR Spectrum

Purity (NMR):

≥94.0%

Applications:

trans,trans-Farnesyl Bromide is a significant reagent and intermediate in organic synthesis, primarily used to introduce the biologically active farnesyl group into other molecules. It holds particular value in constructing complex molecular structures, especially within the fields of biochemical and pharmaceutical chemistry research.

Main Uses:

1. Farnesylation: Used in the preparation of farnesylated compounds such as S-trans,trans-farnesyl-L-cysteine methylester and prenylated peptides.

2. Pharmaceutical Synthesis: Functions as a building block in the research of squalene synthase inhibitors, and as a pharmaceutical intermediate (e.g., vitamins' intermediates).

3. Natural Product Synthesis: Serves as a starting material or intermediate for synthesizing complex natural products, including umbelliprenin, and (±)-farnesiferol A and C.

4. Enzymatic Studies: Employed as a synthetic substrate to investigate the activity of enzymes like guanine nucleotide-binding proteins (G proteins), and used in the preparation of farnesol analogs.

Package: 1/5/10/25kgs/drum

UN number: Not dangerous goods

Store at: Sealed storage in a cool and dry place, avoid light and heat.

Shelf Life: Six months