Methyl (R)-(-)-3-hydroxybutyrate

Product Details

CAS No:3976-69-0

MF:C5H10O3

Appearance:colorless or light-yellow transparent liquid

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:MT

Synonyms:METHYL (R)-(-)-3-HYDROXYBUTYRATE;METHYL D-(R)-3-HYDROXYBUTYRATE;(R)-(-)-3-HYDROXYBUTYRIC ACID METHYL ESTER;(R)-3-HYDROXYBUTYRIC ACID METHYL ESTER;(R)-(-)-3-HYDROXY-N-BUTYRIC ACID METHYL ESTER;(R)-(-)-METHYL 3-HYDROXYBUTYRATE;Methyl-D-(R)-beta-hydroxybutyrate;Methyl(R)-(-)-3-Hydroxy-N-butyrate; 3976-69-0; Methyl (R)-(-)-3-hydroxybutyrate; Methyl (R)-3-hydroxybutanoate; Methyl 3-hydroxybutyrate, (-)-; Butanoic acid, 3-hydroxy-, methyl ester, (3R)-; Methyl 3-hydroxybutyrate, (R)-; EINECS 223-610-0; Butanoic acid, 3-hydroxy-, methyl ester, (R)-; CL06316S38; METHYL (-)-3-HYDROXYBUTANOATE; FEMA NO. 4450, (-)-; Methyl (-)-3-hydroxybutyrate; METHYL 3R-HYDROXYBUTYRATE; (3R)-3-HYDROXYBUTANOIC ACID METHYL ESTER; (-)-(3R)-3-HYDROXYBUTANOIC ACID METHYL ESTER; BUTYRIC ACID, 3-HYDROXY-, METHYL ESTER, D-(-)-; RefChem:815510; 223-610-0; (R)-Methyl 3-Hydroxybutanoate; methyl (3R)-3-hydroxybutanoate; Methyl (R)-3-hydroxybutyrate; MFCD00063289; Methyl(R)-(-)-3-hydroxybutyrate; (r)-methyl 3-hydroxybutyrate; (R)-3-hydroxybutyric acid methyl ester; AC7720; Methyl 3-hydroxybutanoate, (R)-(-)-; UNII-CL06316S38; (R)-(-)-3-Hydroxybutyric Acid Methyl Ester; Butanoic acid, 3-hydroxy-, methyl ester, (3R)-; Butanoic acid, 3-hydroxy-, methyl ester, (R)-; Butyric acid, 3-hydroxy-, methyl ester, D-(-)- (8CI); (-)-(3R)-3-Hydroxybutanoic acid methyl ester; (3R)-3-Hydroxybutanoic acid methyl ester; (R)-(-)-3-Hydroxy-; Methyl 3-hydroxybutyra; methyl 3(R)-hydroxybutyrate; methyl 3(R)-hydroxybutanoate; methyl 3-(R)-hydroxybutanoate; methyl (3R)-3-hydroxybutyrate; methyl (R)-3-hydroxy-butyrate; orb2944135; SCHEMBL2544991; methyl (R)-beta-hydroxybutyrate; (R)-3HB; DTXSID201351446; 3-hydroxy-butyric acid methyl ester; (R)-(-)-Methyl 3-hydroxybutyrate; TCL-00022; Methyl (R)-3-hydroxybutyrate, 99%; AKOS005137981; AKOS015920086; CS-W011223; GS-3453; HY-W010507; AC-25565; SY018984; DB-009764; H0705; NS00083677; EN300-135784; F079225; Q27275514; Methyl (R)-3-hydroxybutyrate, puriss., >=99.0% (sum of enantiomers, GC)

Product application:Methyl (R)-(-)-3-hydroxybutyrate,3976-69-0,Methyl (R)-3-hydroxybutyrate,Methyl (3R)-3-hydroxybutanoate,(R)-(-)-3-Hydroxybutyric acid methyl ester,D-Methyl 3-hydroxybutyrate,Chiral beta-hydroxy ester,Carbapenem antibiotic intermediate,4-AA chiral precursor,Statin drug intermediate,Chiral pharmaceutical synthon,Biodegradable polymer monomer,P3HB monomer,Polyhydroxyalkanoate building block,Asymmetric synthesis building block,Flavor and fragrance ester,Optically active ester,High purity Methyl (R)-3-hydroxybutyrate 99.5%,High chiral purity 99.5% ee,CAS 3976-69-0 supplier,Methyl (R)-(-)-3-hydroxybutyrate manufacturer China,Suzhou Health Chemicals chiral building blocks,Methyl (R)-3-hydroxybutyrate wholesale bulk export

 

Methyl (R)-(-)-3-hydroxybutyrate finds widespread and practical utility across commercial chiral pharmaceutical total synthesis, broad-spectrum carbapenem antibiotic manufacturing, cardiovascular statin drug pharmacophore assembly, biodegradable biomaterial polymer engineering, specialty chiral flavor compounding, and advanced asymmetric stereochemical process sectors. In medicinal chemistry and process pharmacology, universally designated as Methyl (3R)-hydroxybutanoate, it serves as a quintessential, optically active C4 chiral pool building block; its molecular framework incorporates a stereodefined (R)-hydroxyl group paired with an electrophilic terminal methyl ester, providing orthogonal reactivity channels for diastereoselective transformations; in the commercial manufacturing of blockbuster carbapenem antibiotics, including meropenem, imipenem, biapenem, and ertapenem, it functions as the critical chiral starting material for synthesizing the essential 4-acetoxyazetidin-2-one (4-AA) core; through regioselective condensation, activation, and stereospecific beta-lactam cyclization, it installs the requisite (R)-hydroxyethyl chiral auxiliary onto the azetidinone ring with minimal racemization, imparting durable stability against bacterial beta-lactamase degradation and broad-spectrum antimicrobial potency; in metabolic disease therapeutics, it provides the stereogenic building blocks required for assembling the chiral dihydroxy heptanoic acid side chains that characterize competitive HMG-CoA reductase statin inhibitors; in advanced biomaterials science and regenerative tissue engineering, it is utilized as an ultra-pure chiral monomer for synthesizing homochiral poly-(R)-3-hydroxybutyrate (P3HB) and tailor-made polyhydroxyalkanoate (PHA) copolymers; these bio-based matrices undergo enzymatic hydrolytic cleavage in human physiological environments to yield natural endogenous ketone metabolites without inflammatory cytotoxicity, making them ideal for sustained-release microencapsulated injectable drug delivery systems, bioresorbable surgical monofilament sutures, and vascular regeneration scaffolds; in the flavor and fragrance industry, its clean, subtle, and natural fruity organoleptic profile makes it a specialized chiral nuance modifier in beverage and confectionery aroma blending; furthermore, in asymmetric catalysis and stereoselective organic synthesis, Methyl (R)-(-)-3-hydroxybutyrate operates as an essential chiral synthon for developing chiral auxiliary auxiliaries, functional organometallic catalysts, and specialty liquid crystal components delivering exceptional enantiomeric fidelity and consistent performance across industries.