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CAS No:59279-60-6
MF:C12H21NO6
Appearance:white or off-white fine powder
Specification:98.5%
Package:1/5/10/25kgs/drum
Supply Capacity:Tons
Synonyms:(R)-N-Boc-glutamic acid-1,5-dimethyl ester; Dimethyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate; BOC-L-GLU(OME)-OME;BOC-L-GLUTAMIC ACID DIMETHYL ESTER;1,5-dimethyl (2S)-2-{[(tert-butoxy)carbonyl]amino}pentanedioate;(R)-N-Boc-glutamic acid-1,5-dinethyl ester;BOC-GLU(OME)-OME;Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate;BOC-GLU(OME)-OME 45G;N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DI-METHYL DIESTER; Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate,"59279-60-6; dimethyl N-(tert-butoxycarbonyl)-L-glutamate; DTXSID40370416; 1,5-Dimethyl N-((1,1-dimethylethoxy)carbonyl)-L-glutamate; 1,5-Dimethyl N-[(1,1-dimethylethoxy)carbonyl]-L-glutamate; DTXCID70321451; 858-937-3; Boc-Glu(OMe)-OMe; N-Boc-L-Glutamic Acid dimethyl ester; (S)-Dimethyl 2-((tert-butoxycarbonyl)amino)pentanedioate; dimethyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate; N-Boc-L-glutamic acid 1,5-dimethyl ester; MFCD03094774; (S)-2-tert-butoxycarbonylamino-pentanedioic acid dimethyl ester; (S)-2-tert-Butoxycarbonylaminopentanedioic acid dimethyl ester; dimethyl Boc-glutamate; Boc-Glu(OMe)-OMe; Dimethyl (2S)-2-(tert-Butoxycarbonylamino)pentanedioate; Dimethyl N-tert-Butoxycarbonyl-L-glutamate; Methyl (2S)-2-((tert-Butoxycarbonyl)amino)-5-methoxy-5-oxopentanoate; N-tert-Butoxycarbonyl-L-glutamic Acid Dimethyl Ester;; Boc-L-Glu(Ome)-Ome; dimethyl Boc-L-glutamate; L-Glutamic acid, N-[(1,1-dimethylethoxy)carbonyl]-, dimethyl ester; Dimethyl N-Boc-L-glutamate; Boc-Glutamic acid dimethylester; SCHEMBL1763873; dimethyl (2S)-2-(tert-butoxycarbonylamino)pentanedioate; Boc-L-Glutamic acid dimethylester; QNSPKWUAZQIIGZ-QMMMGPOBSA-N; AKOS015918460; CS-W008715; AC-15289; DS-14363; HY-42364; PD196010; SY041419; Dimethyl (tert-butoxycarbonyl)-L-glutamate; N-Boc-L-(+)-glutamic acid dimethyl ester; (R)-N-Boc-glutamicacid-1,5-dimethyl ester; D4536; t-butoxycarbonyl l-glutamic acid dimethyl ester; (S)-dimethyl 2-(tert-butoxycarbonylamino)pentanedioate; (S)-Dimethyl2-((tert-butoxycarbonyl)amino)pentanedioate; N-(tert-Butoxycarbonyl)-L-glutamic Acid Dimethyl Ester; N-alpha-t-Butyloxycarbonyl-L-glutamic acid dimethyl diester; 1,5-DIMETHYL (2S)-2-{[(TERT-BUTOXY)CARBONYL]AMINO}PENTANEDIOATE",275.300,C12H21NO6,;
Application:
N-Boc-L-Glutamic Acid Dimethyl Ester plays a crucial role in organic synthesis as an important amino acid protecting group.
1: N-Boc-L-Glutamic Acid Dimethyl Ester is the key intermediate for PF-07321332(Nirmatrelvir, Paxlovid) (cas#2628280-40-8)
2: N-Boc-L-Glutamic Acid Dimethyl Ester exhibits good solubility and stability, making it a commonly used amino acid protecting group. Its structure contains a protecting group (Boc) and a dimethyl ester group, effectively protecting the carboxyl and amino groups of glutamic acid and preventing unnecessary reactions with other functional groups.
3: N-Boc-L-Glutamic Acid Dimethyl Ester has wide applications in organic synthesis. As an amino acid protecting group, it is frequently used in peptide synthesis, drug synthesis, and other fields. In peptide synthesis, N-Boc-L-Glutamic Acid Dimethyl Ester can serve as a starting amino acid, gradually synthesizing the target peptide through a series of reactions. In drug synthesis, it can serve as an intermediate, participating in the construction and modification of drug molecules.