N-Cbz-L-Glutamic acid 5-tert-butyl ester

Product Details

CAS No:3886-08-6

MF:C17H23NO6

Appearance:white or off-white crystalline powder

Specification:98.5%

UN number:-

Package:1/5/10/25kgs/drum

Supply Capacity:Tons

Synonyms:N-carbobenzyloxy-L-glutamic acid gamma-tert-benzyl ester;N-Cbz-L-glutamic acid γ-t-butyl ester, Z-L-glutamic acid 5-tert-butyl ester;Z-L-GLUTAMIC ACID Y-T-BUTYLESTER;CBZ-L-GLUTAMIC ACID .GAMMA.-TERT.BUTYL ESTER;N-Carbobenzyloxy-L-glutamic acid γ-t.-butyl ester monohydrate;Cbz-L-Glu (γ-But) OH;Z-Glu (But) OH;N-[(Benzyloxy)carbonyl]-L-glutamic acid hydrogen 5-tert-butyl ester; 3886-08-6; EINECS 223-421-3; 5-tert-Butyl N-((phenylmethoxy)carbonyl)-L-glutamate; 5-tert-butyl N-[(phenylmethoxy)carbonyl]-L-glutamate; 5-(1,1-Dimethylethyl) hydrogen N-((phenylmethoxy)carbonyl)-L-glutamate; 5-(1,1-Dimethylethyl) hydrogen N-[(phenylmethoxy)carbonyl]-L-glutamate; RefChem:537834; 223-421-3; Z-Glu(OtBu)-OH; N-Cbz-L-glutamic Acid 5-tert-Butyl Ester; Cbz-Glu(OBut)-OH; (S)-2-(((Benzyloxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid; (2S)-5-[(2-methylpropan-2-yl)oxy]-5-oxo-2-(phenylmethoxycarbonylamino)pentanoic acid; Cbz-L-Glu(otBu)-OH; MFCD00038274; 5-tert-Butyl N-Carbobenzoxy-L-glutamate; 5-tert-Butyl N-Cbz-L-glutamate; M03048; (2S)-4-[(tert-butyl)oxycarbonyl]-2-[(phenylmethoxy)carbonylamino]butanoic acid; Z-Glu(OBut)-OH; Z-(L)Glu(OtBu)-OH; Cbz-(L)Glu(OtBu)-OH; Z-(L)-Glu(OtBu)-OH; (2S)-2-{[(BENZYLOXY)CARBONYL]AMINO}-5-(TERT-BUTOXY)-5-OXOPENTANOIC ACID; SCHEMBL42877; DTXSID001369621; (2S)-2-(benzyloxycarbonylamino)-5-tert-butoxy-5-oxo-pentanoic acid; SBB065851; AKOS015892688; AKOS015924155; CS-W008326; HY-W008326; Cbz-L-glutamic acid 5-tert-butyl ester; AS-12337; BP-12454; SY075420; Z-Glu(OtBu)-OH, >=99.0% (TLC); C1715; ST50826232; EN300-7358417; N-Carbobenzoxy-L-glutamic Acid 5-tert-Butyl Ester; F0001-1101; N-carbobenzyloxy-L-glutamic acid gamma-tert-benzyl ester; N-Benzyloxycarbonyl-L-glutamic acid gamma-tert-butyl ester; (S)-2-Benzyloxycarbonylamino-pentanedioic acid 5-tert-butyl ester; 4(S)-Carboxy-4-(N-(benzyloxycarbonyl)amino)butanoic acid tert-butyl ester

Product application:N-Cbz-L-Glutamic acid 5-tert-butyl ester,3886-08-6,Z-Glu(OtBu)-OH,Cbz-L-Glu(OtBu)-OH,N-Benzyloxycarbonyl-L-glutamic acid 5-tert-butyl ester,Z-L-Glutamic acid gamma-tert-butyl ester,Cbz protected amino acid,Orthogonally protected amino acid,Peptide synthesis building block,Solid phase peptide synthesis reagent,Liquid phase peptide synthesis intermediate,Peptide API raw material,GLP-1 receptor agonist building block,Targeted peptide oncology intermediate,Cosmetic peptide raw material,Anti-aging peptide building block,Chiral pharmaceutical intermediate,Polyglutamic acid biomaterial monomer,Medical hydrogel precursor,High purity Z-Glu(OtBu)-OH 99.5%,N-Cbz-L-Glutamic acid 5-tert-butyl ester manufacturer China,CAS 3886-08-6 supplier,Suzhou Health Chemicals peptide reagents,Z-Glu(OtBu)-OH wholesale bulk export

 

N-Cbz-L-Glutamic acid 5-tert-butyl ester serves as an indispensable, high-purity orthogonally protected chiral amino acid monomer, vital peptide active pharmaceutical ingredient (API) intermediate, and versatile synthetic building block extensively utilized across medicinal therapeutics, cosmetic peptide engineering, biomedical biomaterials, and advanced fine chemical sectors. In commercial peptide pharmaceutical manufacturing and medicinal chemistry, featuring an orthogonal protection design, its alpha-amino benzyloxycarbonyl (Cbz/Z) group can be selectively cleaved via catalytic hydrogenolysis or acidolysis while the gamma-carboxylic tert-butyl ester (OtBu) provides robust steric and electronic shielding against unwanted side reactions such as pyroglutamyl formation and beta-elimination throughout sequential condensation cycles; this unique property makes it a premier synthon in automated solid-phase peptide synthesis (SPPS) and large-scale solution-phase peptide coupling for manufacturing therapeutic peptides targeting metabolic disorders, macrocyclic oncology conjugates, and antimicrobial agents. In cosmeceutical formulation and high-performance skincare, it functions as a critical chiral precursor for synthesizing bioactive anti-aging signal peptides, collagen-stimulating oligopeptides, and epidermal barrier repairing agents. In polymer chemistry and tissue engineering, this monomer is polymerized to synthesize well-defined poly(glutamic acid) block copolymers, pH-responsive targeted drug delivery nanocarriers, and biodegradable surgical hydrogels. In sustainable agrochemicals and specialty chemical synthesis, its chiral framework is utilized to construct bio-inspired antifungal peptidomimetics, asymmetric catalysts, and eco-friendly chelation agents. Furthermore, in functional textile coatings, aqueous polyurethane adhesives, eco-friendly leather finishing auxiliaries, and electronic interfacial modifiers, polymers derived from N-Cbz-L-Glutamic acid 5-tert-butyl ester deliver superior biocompatibility, structural definition, and multifunctional performance.